Risks of phthalate exposure among the general population: implications for occupational health nurses

Details

• Personal Author:
  McCauley LA ; Pak VM
• Description:
  Recently, attention to the prevalence of reproductive and developmental problems in the United States has increased. Mounting evidence demonstrates that environmental chemical exposures may play an important role in these problems. Male reproductive problems, which include undescended testicles and hypospadias, doubled from 1970 to 1993. These reproductive problems increase the risk for testicular cancer (Barret, 2005). The incidence of testicular cancer continues to increase at a rate of 2% to 4% annually in industrialized nations. In the United States, rates have stabilized after 20 years of increasing (Environmental Working Group [EWG], 2000). Recent reports highlight the presence of low-level concentrations of potential carcinogens, plasticizers called phthalates, in personal care products and cosmetics (Barret, 2005). Phthalates are known reproductive and developmental toxicants in animal studies. Swan et al. (2005) recently found a relationship between phthalates and the feminization of U.S. male infants. Colon, Caro, Bourdony, and Rosario (2000) link endocrine-disrupting chemicals like phthalates to the early onset of puberty. These investigators identified Puerto Rican girls with both premature breast development and higher levels of phthalates in their blood. [Description provided by NIOSH]
• Subjects:
  Carcinogens Chemistry Hazardous Substances Infant, Newborn Neoplasms Occupational Health Phthalic Acids Plastics Risk Assessment Risk Factors Safety Urogenital Diseases Urogenital System

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• Keywords:
  Cancer Chemical-properties Chemical-reactions Exposure-levels Hazards Health-hazards Humans Neonates Phthalates Reproduction Reproductive-effects Reproductive-hazards Reproductive-system Reproductive-system-disorders Risk-factors Toxic-effects Toxic-materials Toxins

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• ISSN:
  0891-0162
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  OSHA Region 3 ; Pennsylvania
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  12-17
• Volume:
  55
• Issue:
  1
• NIOSHTIC Number:
  nn:20044955
• Citation:
  AAOHN J 2007 Jan; 55(1):12-17
• Email:
  Vicpak1@yahoo.com
• Federal Fiscal Year:
  2007
• Performing Organization:
  University of Pennsylvania
• Peer Reviewed:
  True
• Start Date:
  20020701
• Source Full Name:
  AAOHN Journal - American Association of Occupational Health Nurses Journal
• End Date:
  20120630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:32d16f781259ec6cb18ca5e6ec3af67f9c57de70d66831a811cddc217920517058d7392cc3bd92a761948b1a6ca0a5296b6ef00821b75de451cb0182fae531ea
• Download URL:
  https://stacks.cdc.gov/view/cdc/200534/cdc_200534_DS1.pdf
• File Type:
  [PDF - 77.82 KB ]