Reduction of PAH Exposure and Effects in Auto Mechanic Trainees: Impact of a Simple Intervention Evaluated by Carcinogen Biological Monitoring

Details

• Personal Author:
  Booth-Jones A ; Goldenhar L ; Lemasters, Grace ; Pinney S ; Talaska G
• Description:
  We have shown previously in an animal model that prompt washing reduces the levels of adducts in skin and lung DNA of mice exposed to engine oil. We used these results to design a simple exposure intervention for a group of young auto mechanic trainees at local technical schools. The intervention consisted of a review of the animal data emphasizing the importance of proper hand washing and care. Hand cleaners (GOJO Industries, Inc. Akron, OH) were provided gratis to the participants. Hand wipes, blood and urine samples were obtained from volunteers at the time of the intervention, and at the end of the study. The levels of polycyclic aromatic compounds (PAC), leukoctye DNA adducts and 1-hydroxypyrene (1HP) were measured in the 3 matrices, respectively. [Description provided by NIOSH]
• Subjects:
  Animals Blood Environmental Exposure Hematologic Tests Hydrocarbons Laboratories Occupational Health Polycyclic Aromatic Hydrocarbons Safety Workplace
• Keywords:
  Animal Studies Blood Samples Exposure Levels Laboratory Animals Leukocytes Polycyclic Aromatic Hydrocarbons Work Environment Workers
• Publisher:
  American Industrial Hygiene Association
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Abstract or Summary
• Place as Subject:
  California ; Ohio ; OSHA Region 5 ; OSHA Region 9
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DSHEFS - Division of Surveillance, Hazard Evaluations, and Field Studies ; EID - Education and Information Division
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  16
• NIOSHTIC Number:
  nn:20022333
• Citation:
  American Industrial Hygiene Conference and Exposition, June 1-6, 2002, San Diego, California. Fairfax, VA: American Industrial Hygiene Association, 2002 Jun; :16
• Federal Fiscal Year:
  2002
• Performing Organization:
  University of Cincinnati
• Peer Reviewed:
  False
• Start Date:
  19920701
• Source Full Name:
  American Industrial Hygiene Conference and Exposition, June 1-6, 2002, San Diego, California
• End Date:
  20070630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:456e11cf502793077889a67e4099c9b632fbac87ad09fa89410ea6e05c8250daa2d0ba87bd1df394a0d5925244a22def14addfa3026ea2cd37f6028672e78d4c
• Download URL:
  https://stacks.cdc.gov/view/cdc/199143/cdc_199143_DS1.pdf
• File Type:
  [PDF - 493.05 KB ]