Blood Pressure, Left Ventricular Mass, and Lead Exposure in Battery Manufacturing Workers

Details

• Personal Author:
  Mueller, Charles A. ; Sagar K ; Singal, Mitchell ; Tepper, Allison L.
• Description:
  Background: Although debate about the relationship between lead and blood pressure has focused on low environmental lead levels, industrial exposure remains a concern. Methods: We measured blood pressure and left ventricular mass (LVM) in 108 battery manufacturing workers, and calculated cumulative and historic average measures of blood lead. Results: Diastolic pressure increased with increasing lead levels, with a significant (P= 0.04) 5 mmHg difference in mean pressure between the highest and lowest cumulative exposure levels. Diastolic pressure increased with the log of cumulative lead (P= 0.06). Both hypertension (defined as currently medicated or systolic greater than 160 mmHg or diastolic greater than 95 mmHg) and LVM increased nonsignificantly with increasing lead exposure (P-values greater than or equal to 0.17 for hypertension and greater than or equal to 0.20 for LVM). Conclusions: We found a small effect of blood lead on diastolic blood pressure, particularly for a cumulative measure of exposure, but no convincing evidence of associations between lead and other blood-pressure-related outcomes. [Description provided by NIOSH]
• Subjects:
  Blood Cardiovascular Diseases Cardiovascular System Environmental Exposure Environmental Pollution Lead Manufacturing And Industrial Facilities Metals, Heavy Occupational Health Safety
• Keywords:
  Author Keywords: Lead Battery-manufacturing-industry Battery Manufacturing Blood-pressure Blood Pressure Cardiovascular-disease Cardiovascular-function Cardiovascular-system Cardiovascular-system-disease Cardiovascular-system-disorders Cardiovascular Disease Environmental-exposure Environmental-pollution Heavy-metals Hypertension Industrial-emissions Industrial-exposures Industrial-factory-workers Lead-absorption Lead-compounds

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• ISSN:
  0271-3586
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  Ohio ; OSHA Region 5 ; Wisconsin
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DSHEFS - Division of Surveillance, Hazard Evaluations, and Field Studies
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  63-72
• Volume:
  40
• Issue:
  1
• NIOSHTIC Number:
  nn:20021891
• Citation:
  Am J Ind Med 2001 Jul; 40(1):63-72
• Contact Point Address:
  AllisonTepper, PhD, Division of Surveillance, Hazard Evaluations, and Field Studies,National Institute for Occupational Safety and Health, 4676 Columbia Parkway R-10, Cincinnati, OH 45226
• Email:
  atepper@cdc.gov
• CAS Registry Number:
  Lead (CAS RN 7439-92-1)
• Federal Fiscal Year:
  2001
• Peer Reviewed:
  True
• Source Full Name:
  American Journal of Industrial Medicine
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:56309e45108afb69b8c513306cc157ed985600ba3a70dfbeb4a73013de6130b2cee60d260ba40030331c56f89792df686cb94354b106e93ac0c45c2d383bb9da
• Download URL:
  https://stacks.cdc.gov/view/cdc/198977/cdc_198977_DS1.pdf
• File Type:
  [PDF - 118.30 KB ]