Involvement of Sphingomyelinase in Insulin-Induced Phosphatidylinositol 3-Kinase Activation

Details

• Personal Author:
  Bode AM ; Castranova, Vincent ; Ding M ; Dong Z ; Huang C ; Li J ; Ma WY ; Shi X ; Vallyathan V
• Description:
  SPECIFIC AIM- This manuscript aims to elucidate the mechanism by which insulin activates phosphatidylinositol 3-kinase (PI-3 kinase), especially the role of sphingomyelinase (SMase) in insulin-induced PI-3 kinase activation. [Description provided by NIOSH]
• Subjects:
  Animals Laboratories Occupational Health Phosphoric Acids Safety
• Keywords:
  Animal-studies Author Keywords: Ceramide Cell-growth Laboratory-animals Laboratory-testing Niemann-Pick Disease Phosphates Proteins Signal Transduction
• ISSN:
  0892-6638
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  Minnesota ; OSHA Region 3 ; OSHA Region 5 ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  HELD - Health Effects Laboratory Division
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  15
• Issue:
  6
• NIOSHTIC Number:
  nn:20021756
• Citation:
  FASEB J 2001 Apr; 15(6):1113-1114
• Federal Fiscal Year:
  2001
• NORA Priority Area:
  Work Environment and Workforce: Mixed Exposures
• Peer Reviewed:
  True
• Source Full Name:
  The FASEB Journal
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:81e99220d2785b4d03b3dd04ee8e7ecc47bdf1ef2efcd152a66c1711ea0e4348334629f5e066aa314961ad731ca35f1068ddef4febc926a9201d9b702d5fb851
• Download URL:
  https://stacks.cdc.gov/view/cdc/198865/cdc_198865_DS1.pdf
• File Type:
  [PDF - 434.93 KB ]