Neurophysiological Function in Farm Workers Exposed to Organophosphate Pesticides

Details

• Personal Author:
  Checkoway, Harvey ; Engel LS ; Keifer MC ; Robinson LR ; Vaughan TL
• Description:
  To investigate neurophysiological effects of low-level exposure to foliar organophosphate residues during one season among agricultural workers, the authors performed a cross-sectional study of 67 Hispanic farm workers and 68 age-, gender-, ethnicity-, and education-matched reference subjects. The neurophysiological examination included sensory and motor nerve conduction and neuromuscular junction testing. Erythrocyte cholinesterase activity was measured at the time of examination. No statistically significant neurophysiological differences between the exposed and reference groups were observed. Farm workers and reference subjects had similar sensory nerve latency and amplitude (sural), motor nerve conduction velocity (ulnar), and neuromuscular junction function (ulnar). No relationship between duration of exposure during the season and electrophysiological measures of nerve function was found. Exposure of farm workers to the low levels of organophosphate pesticides during one season experienced by farm workers in this study was not associated with impaired peripheral neurophysiological function. [Description provided by NIOSH]
• Subjects:
  Agriculture Farmers Insecticides Nervous System Nervous System Diseases Occupational Health Organophosphates Safety
• Keywords:
  Agricultural-chemicals Agricultural-workers Nerve-function Neurological-reactions Neurological-system Neuromotor-system-disorders Neuromuscular-system-disorders Neurophysiological-effects Neurophysiology Neurotoxic-effects Neurotoxins Organo-phosphorus-pesticides Pesticides Pesticides-and-agricultural-chemicals Worker-health Workers

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• ISSN:
  0003-9896
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  OSHA Region 10 ; Washington
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  7-14
• Volume:
  53
• Issue:
  1
• NIOSHTIC Number:
  nn:20001019
• Citation:
  Arch Environ Health 1998 Jan; 53(1):7-14
• Contact Point Address:
  Department of Epidemiology, University of Washington, Seattle, Washington
• Federal Fiscal Year:
  1998
• NORA Priority Area:
  Work Environment And Workforce: Special Populations
• Performing Organization:
  Department of Medicine & Environmental Health, school of Medicine, University of Washington
• Peer Reviewed:
  True
• Start Date:
  19930901
• Source Full Name:
  Archives of Environmental Health
• End Date:
  19970831
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:6e8dbb5ac3a2db539dccd65ae1bd848357bb10173e2105ac89d3b9ef209f22cd1725c39ea3eab4fae3eb53f329a80c84c2fdda20b01aac60c3b2bee6b13b8c6e
• Download URL:
  https://stacks.cdc.gov/view/cdc/198297/cdc_198297_DS1.pdf
• File Type:
  [PDF - 867.73 KB ]