Paternal Occupational Exposure to 2,3, 7,8-Tetrachlorodibenzo-P-Dioxin and Birthweight of Offspring

Details

• Personal Author:
  Connally LB ; Dankovic, David A. ; Deddens JA ; Lawson, Christina C. ; Piacitelli, Laurie A. ; Schnorr, Teresa M. ; Sweeney, Marie H. ; Whelan, Elizabeth A.
• Description:
  Agent Orange, a phenoxy herbicide, is a SO/50 mixture of the herbicides 2,4-D [(2,4-dichlorophenoxy)acetic acid] and 2,4,5-T [(2,4,5-trichlorophenoxy)acetic acid], which was contaminated with 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). There have been few studies of paternal TCDD exposure and birthweight. The National Academy of Sciences (NAS) concluded there was insufficient or inadequate evidence to determine whether there is an association. We studied the pregnancy outcomes among wives of male workers highly exposed to chemicals contaminated with TCDD and among wives of non-exposed neighborhood referents that participated in a cross-sectional medical study. In the current paper we evaluate the association between paternal exposure to TCDD at the time of conception and birthweight of offspring. [Description provided by NIOSH]
• Subjects:
  Dioxins Epidemiology Herbicides Occupational Health Safety Urogenital Diseases Urogenital System
• Keywords:
  Reproductive-effects Reproductive-hazards Statistical-analysis
• ISBN:
  3928379194
• Document Type:
  Text
• Genre:
  Proceedings
• Place as Subject:
  Massachusetts ; Ohio ; OSHA Region 1 ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DSHEFS - Division of Surveillance, Hazard Evaluations, and Field Studies
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  1-4
• Volume:
  64
• NIOSHTIC Number:
  nn:20024145
• Citation:
  Dioxin 2003, 23rd International Symposium on Halogenated Environmental Organic Pollutants and POPs, August 24-29, 2003, Boston, Massachusetts. Boston, MA: RPJ Associates, 2003 Aug; 64:1-4
• Contact Point Address:
  National Institute for Occupational Safety and Health, 4676 Columbia Pkwy, Cincinnati, OH 45226
• CAS Registry Number:
  (2,4-Dichlorophenoxy)acetic acid (CAS RN 94-75-7) ; 2,3,7,8-Tetrachlorodibenzo-p-dioxin (CAS RN 1746-01-6) ; Phenol, trichloro-, sodium salt (1:1) (CAS RN 1320-79-2) ; Trichlorophenoxyacetic acid (CAS RN 93-76-5)
• Federal Fiscal Year:
  2003
• Peer Reviewed:
  False
• Source Full Name:
  Dioxin 2003, 23rd International Symposium on Halogenated Environmental Organic Pollutants and POPs, August 24-29, 2003, Boston, Massachusetts
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:6b02a95d4c7f5c477b9eadff934bec99131fcd16a2e8d425e56d5aa41e501301c400a7958621ccbf11e06d708644d61aa59f21024235120fa7959fbc1cb98253
• Download URL:
  https://stacks.cdc.gov/view/cdc/196110/cdc_196110_DS1.pdf
• File Type:
  [PDF - 597.88 KB ]