Development of Colorimetric Indicators: A New Technique to Determine Glutaraldehyde and Alkaline Glutaraldehyde Contamination

Details

• Personal Author:
  Vo E
• Description:
  The aim of the study was to investigate a new indicator sensor pad for detection of glutaraldehyde permeation of chemical protective gloves. The pad carries a reagent which responds to glutaraldehyde contaminant by producing a color change. Some commonly used glutaraldehyde and alkaline glutaraldehyde solutions, Metricide, Cetylcide-G, and 50% glutaraldehyde solution, were analyzed by solvent desorption and gas chromatography. All glutaraldehyde solutions exhibited >98% adsorption on the pads over the spiking range 0.05-5.0 mL. Recovery for each glutaraldehyde solution was calculated, ranging from 58-92% (RSD <=4.0%) for all glutaraldehyde solutions. Breakthrough times for two protective glove materials (PVC and polymerized alkene) were determined using the Thermo-Hand Method, and found to range from 76 to 150 min for Metricide, from 170 to 230 min for Cetylcide-G, and from 232 to 300 min for 50% glutaraldehyde. The quantitative mass of the glutaraldehyde solutions on the pads at the time of breakthrough detection ranged from 35-37, 37-39, and 38-40 mg/cm2 for Metricide, Cetylcide-G, and 50% glutaraldehyde, respectively. The new aldehyde indicator pad should find utility in detecting, collecting, and quantitative analyzing glutaraldehyde and alkaline glutaraldehyde permeation samples in the workplace. [Description provided by NIOSH]
• Subjects:
  Occupational Health Personal Protective Equipment Protective Clothing Safety Solvents
• Keywords:
  Gas Liquid Chromatography Gloves Personal Protective Equipment Protective Clothing Protective Equipment Samplers Sampling Equipment Sampling Methods Solvent Extraction
• Publisher:
  National Institute for Occupational Safety and Health
• Document Type:
  Text
• Genre:
  Abstract or Summary
• Place as Subject:
  OSHA Region 3 ; Pennsylvania
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  NPPTL - National Personal Protective Technology Laboratory
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  29
• NIOSHTIC Number:
  nn:20023335
• Citation:
  Working Partnerships: Applying Research to Practice, NORA Symposium 2003, June 23-24, 2003, Arlington, Virginia. Washington, DC: National Institute for Occupational Safety and Health, 2003 Jun; :29
• Federal Fiscal Year:
  2003
• NORA Priority Area:
  Disease and Injury: Allergic and Irritant Dermatitis
• Peer Reviewed:
  False
• Source Full Name:
  Working Partnerships: Applying Research to Practice, NORA Symposium 2003, June 23-24, 2003, Arlington, Virginia
• End Date:
  20060930
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:9b5111733df2a94755ddca1d2ed0cdd48b0e64f3b8416f5906cd4f342ae0a38125ec5fc036234a53174ad252de896ea7d801a529c7ddd47ffbb4b38e02699d10
• Download URL:
  https://stacks.cdc.gov/view/cdc/195838/cdc_195838_DS1.pdf
• File Type:
  [PDF - 167.44 KB ]