Exposure to Endosulfan in Farmers: Two Case Studies

Details

• Personal Author:
  Brandt VA ; Ehlers J ; Methner, Mark M. ; Moon S ; Struttmann, Timothy
• Description:
  Endosulfan is not a restricted use organochlorine insecticide and is currently under re-registration review. In 1993, one confirmed case and one possible case of endosulfan poisoning in agricultural workers occurred in two southeastern states. Two cases of suspected endosulfan poisoning were investigated utilizing record reviews, blood samples, a site visit, and clothing analysis. Case 1 was fatal; Case 2 resulted in permanent neurological impairment. Additionally, Case 1 mixed and applied two less toxic pesticides, acephate and maleic hydrazide to tobacco plants. Both farm owners had ample opportunity for endosulfan exposure while mixing concentrated endosulfan with water and applying the solution to tobacco with boom sprayers pulled by tractors. Estimates of the absorbed dose of endosulfan were not available because methods to determine actual personal exposure that would be found in fat or tissue samples were not used. Health and safety issues associated with endosulfan require a closer examination. A cooperative multi-disciplinary approach to providing timely accurate education is needed to prevent pesticide poisonings. [Description provided by NIOSH]
• Subjects:
  Agriculture Blood Farmers Hematologic Tests Insecticides Nervous System Occupational Exposure Occupational Health Personal Protective Equipment Poisoning Respiratory Tract Diseases Safety Tobacco Products

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• Keywords:
  Agricultural Workers Agriculture Author Keywords: Endosulfan Blood Sampling Clothing Convulsions Neurological Reactions Neurotoxins Occupational Exposure Organo Chlorine Compounds Personal Protective Equipment Pesticide Pesticides Pesticides And Agricultural Chemicals Poisoning Poisons Protective Equipment Public Health Respiratory System Disorders Tobacco

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• ISSN:
  0271-3586
• Document Type:
  Text
• Funding:
  Cooperative Agreement
• Genre:
  Journal Article
• Place as Subject:
  Kentucky ; North Carolina ; Ohio ; OSHA Region 4 ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DSHEFS - Division of Surveillance, Hazard Evaluations, and Field Studies
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  39
• Issue:
  6
• NIOSHTIC Number:
  nn:20023301
• Citation:
  Am J Ind Med 2001 Jun; 39(6):643-649
• Contact Point Address:
  Victoria A. Brandt, BS, RN, Community Partners for Healthy Farming Project, 745 Shaker Mill Road, Bowling Green, Kentucky 42103
• CAS Registry Number:
  Acephate (CAS RN 30560-19-1) ; Endosulfan (mixed isomers) (CAS RN 115-29-7) ; Maleic hydrazide (CAS RN 123-33-1)
• Federal Fiscal Year:
  2001
• Performing Organization:
  Kentucky Injury Prevention and Research Center, University of Kentucky, Lexington, Kentucky
• Peer Reviewed:
  True
• Start Date:
  19960930
• Source Full Name:
  American Journal of Industrial Medicine
• End Date:
  20000929
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:b69b51fd49998216c23d1bc39a96f9f9fc4d2f3cd5b68330edd144c2c22932e98055d3be689dcb0e066b42a595dda9410765ff18f977b2f7ed611ffa75c43061
• Download URL:
  https://stacks.cdc.gov/view/cdc/195816/cdc_195816_DS1.pdf
• File Type:
  [PDF - 97.88 KB ]