Associations between insulin and heart rate variability in police officers

Details

• Personal Author:
  Andrew, Michael E. ; Burchfiel CM ; Charles LE ; Gu JK ; Li S ; Miller DB ; Mnatsakanova A ; Sarkisian K ; Violanti JM ; Wilson M
• Description:
  OBJECTIVE: Low heart rate variability (HRV) has been linked to cardiovascular disease. Our objective was to examine the cross-sectional association between insulin and HRV. METHODS: Insulin levels were measured in 355 nondiabetic officers from the BCOPS study, following a 12 h fast. HRV was performed according to methods published by the task force of the European Society of Cardiology and the North American Society of Pacing Electrophysiology for measurement and analysis of HRV. Mean values of high (HF) and low frequency (LF) HRV were compared across tertiles of insulin using ANOVA and ANCOVA; p-values were obtained from linear regression models. RESULTS: Higher mean levels of insulin were significantly associated with lower (i.e., worse) mean levels of HRV before and after risk-factor adjustment. The results for HF HRV (ms2) were as follows: 1st insulin (microU/ml) tertile (156.3; 95% confidence interval (CI) = 128.6-189.9); 2nd tertile (154.3; 95% CI = 124.3-191.5); 3rd tertile (127.9; 95% CI = 105.0-155.8), p for trend = 0.017. Results with LF HRV were similar to HF HRV. Insulin was also inversely and significantly associated with HRV among officers with BMI >/=25 kg/m2, with >/=25.5% body fat, and among those who reported low (
• Subjects:
  Body Weight Cardiovascular Diseases Cardiovascular System Electrophysiology Emergencies Endocrine System Energy Metabolism Law Enforcement Occupational Health Periodicity Risk Assessment Risk Factors Safety

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• Keywords:
  Autonomic-nervous-system Biological-rhythms Body-weight Cardiovascular-disease Cardiovascular-function Drug-interaction Electrophysiological-effects Electrophysiological-measurements Emergency-response Employee-health Heart Heart-rate Hormone-activity Law-enforcement Mathematical-models Metabolic-activation Physical-exercise Police-officers Risk-factors Weight-factors Weight-measurement

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• ISSN:
  1042-0533
• Document Type:
  Text
• Funding:
  Grant ; Contract
• Genre:
  Journal Article
• Place as Subject:
  Illinois ; New York ; OSHA Region 2 ; OSHA Region 3 ; OSHA Region 5 ; Pennsylvania ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  HELD - Health Effects Laboratory Division
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  56-63
• Volume:
  26
• Issue:
  1
• NIOSHTIC Number:
  nn:20043301
• Citation:
  Am J Hum Biol 2014 Jan/Feb; 26(1):56-63
• Contact Point Address:
  Luenda E. Charles, National Institute for Occupational Safety and Health, HELD/BEB, MS L-4050, 1095 Willowdale Rd., Morgantown, WV 26505-2888
• Email:
  lcharles@cdc.gov
• Federal Fiscal Year:
  2014
• NORA Priority Area:
  Public Safety
• Performing Organization:
  State University of New York at Buffalo
• Peer Reviewed:
  True
• Start Date:
  20100901
• Source Full Name:
  American Journal of Human Biology
• End Date:
  20150831
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:3a9df10dfb10635a56eba687ab6c4c94b851fc1f50708846513091012aa7117d59216ca9a6a6bc3bedcb2b865807fe56afb6944949051813e0b19f4b63fbde1d
• Download URL:
  https://stacks.cdc.gov/view/cdc/195228/cdc_195228_DS1.pdf
• File Type:
  [PDF - 103.63 KB ]