Molecular and epidemiologic predictors of Staphylococcus aureus colonization site in a population with limited nosocomial exposure

Details

• Personal Author:
  Forshey BM ; Hanson BM ; Moritz ED ; Smith TC ; Wardyn SE
• Description:
  BACKGROUND: The anterior naris has been considered the most consistent location of asymptomatic Staphylococcus aureus colonization. However, recent studies have shown that a substantial number of individuals, ranging from 7% to 32% of colonized individuals, are exclusive throat carriers. Most of these studies have been carried out in a health care setting, limiting their generalizability to nonhospitalized populations. METHODS: To evaluate anatomic carriage sites of S aureus in individuals outside of a health care setting, we combined the results of 2 cross-sectional studies conducted in Iowa. RESULTS: S aureus was carried by 103 of 340 individuals (30.3%), including 31 (30.1%) exclusive throat carriers, 44 (42.7%) exclusive nose carriers, and 28 (27.2%) colonized in both sites. Nonwhite race (adjusted odds ratio [OR], 4.91; 95% confidence interval [CI], 1.26-18.3) and younger age (≤=30 years: OR, 0.23; 95% CI, 0.10-0.54) were associated with increased odds of exclusive throat carriage, whereas nonwhite race (OR, 5.14; 95% CI, 1.62-16.3) and spring or summer sampling season (OR, 2.62; 95% CI, 1.32-5.18) were associated with increased odds of exclusive nasal carriage. CONCLUSIONS: These findings suggest that including a throat swab in addition to a nasal swab could play an important role in the success of surveillance programs, particularly among younger adults. [Description provided by NIOSH]
• Subjects:
  Bacterial Infections Epidemiology Microbiology Occupational Health Safety
• Keywords:
  Anatomic Location Author Keywords: Bacterial Carriage Bacterial-disease Bacterial-infections Body Site Cross Sectional Studies Molecular-biology Surveillance Throat
• ISSN:
  0196-6553
• Document Type:
  Text
• Funding:
  Grant ; Cooperative Agreement
• Genre:
  Journal Article
• Place as Subject:
  Iowa ; Maryland ; OSHA Region 3 ; OSHA Region 7
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  40
• Issue:
  10
• NIOSHTIC Number:
  nn:20042538
• Citation:
  Am J Infect Control 2012 Dec; 40(10):992-996
• Contact Point Address:
  Tara C. Smith PhD, 105 River Street, S431 CPHB, Iowa City, IA 52242
• Email:
  tara-smith@uiowa.edu
• Federal Fiscal Year:
  2013
• NORA Priority Area:
  Agriculture, Forestry and Fishing
• Performing Organization:
  University of Iowa
• Peer Reviewed:
  True
• Start Date:
  20050701
• Source Full Name:
  American Journal of Infection Control
• End Date:
  20290630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:e965adce800516245a88f85154e4effcc30ab326bafd702f8f95445b55392429856c39dac9ab8a3a047a6a7bdca44399476be4e9378ca69a22b1ed15eb6d7307
• Download URL:
  https://stacks.cdc.gov/view/cdc/194727/cdc_194727_DS1.pdf
• File Type:
  [PDF - 139.27 KB ]