Evaluation of chemotherapy drug exposure at a veterinary teaching hospital in Michigan

Details

• Personal Author:
  Connor, Thomas H. ; Couch, James R. ; Gibbins J
• Description:
  In February 2010, the National Institute for Occupational Safety and Health (NIOSH) received a confidential employee request for a Health Hazard Evaluation (HHE) at a veterinary teaching hospital that provides routine care and oncology services to large and small animals. Canines and felines constitute the majority of the oncology department's patients. Veterinary hospital employees were concerned about adverse health effects from the use of chemotherapy drugs in the oncology department. In 2004, NIOSH released an Alert regarding occupational exposures to antineoplastic and other hazardous drugs that are used in health care settings. Hazardous drugs were defined in the NIOSH Alert as having "specific health effects (such as skin rashes, cancer, and reproductive effects) and high toxicity at low doses." The NIOSH Alert also described best practices for handling, storage, disposal, and decontamination procedures and was updated in 2010 and 2012 to include an expanded list of hazardous drugs. Also in 2010, NIOSH released a Workplace Solutions document to increase awareness of occupational safety and health issues in veterinary health care workers who work with antineoplastic and hazardous drugs. [Description provided by NIOSH]
• Subjects:
  Animals Antineoplastic Agents Drug Therapy Hazardous Substances Health Personnel Manufacturing And Industrial Facilities Neoplasms Occupational Exposure Occupational Health Personal Protective Equipment Safety Skin Urogenital Diseases Urogenital System Veterinarians Waste Management

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• Keywords:
  Antineoplastic-agents Biological-effects Cancer Chemotherapy Decontamination Drug-therapy Drugs Employee-exposure Hazardous-materials Health-hazards HETA 2008-0091-3118 Materials-handling Materials-storage Occupational-exposure Oncogenic-agents Personal-protective-equipment Reproductive-effects Reproductive-hazards Skin-irritants Toxic-effects Toxic-materials Veterinary-medicine Waste-disposal Work-practices Worker-health

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• ISSN:
  1545-9624
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  Michigan ; Ohio ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DSHEFS - Division of Surveillance, Hazard Evaluations, and Field Studies ; DART - Division of Applied Research and Technology
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  10
• Issue:
  4
• NIOSHTIC Number:
  nn:20042269
• Citation:
  J Occup Environ Hyg 2013 Apr; 10(4):D45-D51
• Contact Point Address:
  James Couch, NIOSH, 4676 Columbia Parkway, MS R-11, Cincinnati, OH 45226
• Email:
  JCouch@cdc.gov
• CAS Registry Number:
  Cyclophosphamide (CAS RN 50-18-0) ; Doxorubicin (CAS RN 23214-92-8) ; Ifosfamide (CAS RN 3778-73-2)
• Editor(s):
  Larranaga M
• Federal Fiscal Year:
  2013
• NORA Priority Area:
  Healthcare and Social Assistance
• Peer Reviewed:
  True
• Source Full Name:
  Journal of Occupational and Environmental Hygiene
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:0ba280d7ad2b920aa92f27e8f23b7785794b96dadbba8ba44ff1239774d82d7c587ff0f3e961574905b115a1990848b534703250c0eb542119bec179a0842a53
• Download URL:
  https://stacks.cdc.gov/view/cdc/194547/cdc_194547_DS1.pdf
• File Type:
  [PDF - 404.12 KB ]