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Revised Recommended Standard: Occupational Exposure to Ethylene Dichloride (1,2-Dichloroethane)
  • Published Date:
    September 1978
  • Status:
    current
Filetype[PDF - 549.52 KB]


Details:
  • Corporate Authors:
    National Institute for Occupational Safety and Health
  • Document Type:
  • Description:
    In 1975, a criteria document containing the recommended standard for occupational exposure to ethylene dichloride (1,2-dichloroethane) was prepared by NIOSH. In that document, NIOSH recommended that the present Federal occupational health standard of 50 parts per million (ppm), determined as an 8-hour time-weighted average (TWA), be reduced to a TWA of 5 ppm for a 10-hour workshift, 40-hour workweek. NIOSH based its recommendations on a wide range of potentially serious health effects involving the nervous, respiratory, hepatic, and cardiovascular systems. NIOSH also expressed concern regarding the potential carcinogenicity of one possible metabolite of ethylene dichloride and noted the carcinogenic study being conducted by the National Cancer Institute. This recently completed study has demonstrated that ethylene dichloride is carcinogenic in rats and mice.

    NIOSH recommends, on the basis of the study and on the basis of studies demonstrating mutagenicy, that ethylene dichloride be controlled as an occupational carcinogen and that the previous recommended standard be revised downward from 5 ppm (20 mg/cu m), to 1 ppm (4 mg/cu m) determined as a TWA exposure for up to a 10-hour workshift. NIOSH further recommends a ceiling concentration of 2 ppm (8 mg/cu m) as determined over a 15-minute sampling period. In 1975, a criteria document containing the recommended standard for occupational exposure to ethylene dichloride (1,2-dichloroethane) was prepared by NIOSH. In that document, NIOSH recommended that the present Federal occupational health standard of 50 parts per million (ppm), determined as an 8-hour time-weighted average (TWA), be reduced to a TWA of 5 ppm for a 10-hour workshift, 40-hour workweek. NIOSH based its recommendations on a wide range of potentially serious health effects involving the nervous, respiratory, hepatic, and cardiovascular systems. NIOSH also expressed concern regarding the potential carcinogenicity of one possible metabolite of ethylene dichloride and noted the carcinogenic study being conducted by the National Cancer Institute. This recently completed study has demonstrated that ethylene dichloride is carcinogenic in rats and mice.

    NIOSH recommends, on the basis of the study and on the basis of studies demonstrating mutagenicy, that ethylene dichloride be controlled as an occupational carcinogen and that the previous recommended standard be revised downward from 5 ppm (20 mg/cu m), to 1 ppm (4 mg/cu m) determined as a TWA exposure for up to a 10-hour workshift. NIOSH further recommends a ceiling concentration of 2 ppm (8 mg/cu m) as determined over a 15-minute sampling period. In 1975, a criteria document containing the recommended standard for occupational exposure to ethylene dichloride (1,2-dichloroethane) was prepared by NIOSH. In that document, NIOSH recommended that the present Federal occupational health standard of 50 parts per million (ppm), determined as an 8-hour time-weighted average (TWA), be reduced to a TWA of 5 ppm for a 10-hour workshift, 40-hour workweek. NIOSH based its recommendations on a wide range of potentially serious health effects involving the nervous, respiratory, hepatic, and cardiovascular systems. NIOSH also expressed concern regarding the potential carcinogenicity of one possible metabolite of ethylene dichloride and noted the carcinogenic study being conducted by the National Cancer Institute. This recently completed study has demonstrated that ethylene dichloride is carcinogenic in rats and mice.

    NIOSH recommends, on the basis of the study and on the basis of studies demonstrating mutagenicy, that ethylene dichloride be controlled as an occupational carcinogen and that the previous recommended standard be revised downward from 5 ppm (20 mg/cu m), to 1 ppm (4 mg/cu m) determined as a TWA exposure for up to a 10-hour workshift. NIOSH further recommends a ceiling concentration of 2 ppm (8 mg/cu m) as determined over a 15-minute sampling period. In 1975, a criteria document containing the recommended standard for occupational exposure to ethylene dichloride (1,2-dichloroethane) was prepared by NIOSH. In that document, NIOSH recommended that the present Federal occupational health standard of 50 parts per million (ppm), determined as an 8-hour time-weighted average (TWA), be reduced to a TWA of 5 ppm for a 10-hour workshift, 40-hour workweek. NIOSH based its recommendations on a wide range of potentially serious health effects involving the nervous, respiratory, hepatic, and cardiovascular systems. NIOSH also expressed concern regarding the potential carcinogenicity of one possible metabolite of ethylene dichloride and noted the carcinogenic study being conducted by the National Cancer Institute. This recently completed study has demonstrated that ethylene dichloride is carcinogenic in rats and mice.

    NIOSH recommends, on the basis of the study and on the basis of studies demonstrating mutagenicy, that ethylene dichloride be controlled as an occupational carcinogen and that the previous recommended standard be revised downward from 5 ppm (20 mg/cu m), to 1 ppm (4 mg/cu m) determined as a TWA exposure for up to a 10-hour workshift. NIOSH further recommends a ceiling concentration of 2 ppm (8 mg/cu m) as determined over a 15-minute sampling period.

  • Supporting Files:
    No Additional Files