The value of periodic spirometry for early recognition of long-term excessive lung function decline in individuals

Details

• Personal Author:
  Hnizdo, Eva
• Description:
  OBJECTIVE: To establish the value of workplace spirometry monitoring methods for early recognition of long-term excessive lung function decline in individuals. METHODS: Sensitivity, specificity, and positive likelihood ratio were calculated to determine the predictive value of the linear regression slope and limits of longitudinal decline for early prediction of long-term excessive forced expiratory volume in 1 second (FEV1) decline (> 90 mL/yr established over 9 to 11 years) in ongoing spirometry monitoring programs (firefighters and construction workers) and a historical program (paper-pulp mill workers). The longitudinal limits account for the expected FEV1 within-person variability. RESULTS: The longitudinal limits achieved clinical "usefulness" (positive likelihood ratio 10 or higher) from the fourth to fifth year of follow-up, whereas the linear regression slope was less useful. The usefulness depended on data precision and measurement frequency. CONCLUSION: The limits of longitudinal decline are more useful for early recognition of long-term excessive FEV1 decline than the linear regression slope. [Description provided by NIOSH]
• Subjects:
  Construction Industry Firefighters Lung Men Occupational Health Paper Respiratory Function Tests Respiratory System Safety Women
• Keywords:
  Construction-workers Fire-fighters Humans Lung-function Monitoring-systems Paper-milling Spirometry Surveillance
• ISSN:
  1076-2752
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  OSHA Region 3 ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DRDS - Division of Respiratory Disease Studies
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  54
• Issue:
  12
• NIOSHTIC Number:
  nn:20041761
• Citation:
  J Occup Environ Med 2012 Dec; 54(12):1506-1512
• Contact Point Address:
  Eva Hnizdo, PhD, Division of Respiratory Disease Studies, National Institute for Occupational Safety and Health, 1095 Willowdale Rd, Morgantown, WV 26505
• Email:
  ehnizdo@cdc.gov
• Federal Fiscal Year:
  2013
• Peer Reviewed:
  True
• Source Full Name:
  Journal of Occupational and Environmental Medicine
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:404c2c0bcdc1a96a15ad248c676ccc116d1a3b5175b69eb84d356dedfc4150dd5aa826b7bf7ed8dff9a0c51eaa66c4d4b0dc3cb59394784ef540d19b7ba81a5c
• Download URL:
  https://stacks.cdc.gov/view/cdc/194235/cdc_194235_DS1.pdf
• File Type:
  [PDF - 589.55 KB ]