"The report reviews current toxicity information on 4,4'-methylenebis (2-chloroaniline) and makes control recommendations. 4,4'-methylenebis (2-chloroaniline) has the formula C13H12C12N2. it is commercially important as a curing agent for diisocyanate-based polymers (polyurethanes) and epoxy resin systems. 4,4'-methylenebis (2-chloroaniline) is used to vary the hardness, flexibility, and impact strength of these products. 4,4'-methylenebis(2-chloroaniline) has been manufactured commercially in the u.s. since 1956. above 200 degrees C, 4,4'-methylenebis(2-chloroaniline), releases irritant and toxic vapors (primarily ortho-chloroaniline). NIOSH estimated through a national survey that in the early 1970's approximately 55,000 u.s. workers were potentially exposed to 4,4'-methylenebis(2-chloroaniline). the majority of these workers were employed in small-to-medium sized establishments where occupational health services may not have been readily available. this review provides an examination of information available in 1973 and a more detailed presentation of recent studies along with recommendations for control of workplace exposures to 4,4-methylenebis(2-chloroaniline)." - NIOSHTIC-2

NIOSHTIC no. 20000299

Stephen B. Thacker CDC Library collection
Guidelines and Recommendations