Evaluation of immune responses

Details

• Personal Author:
  Schulte, Paul A. ; Vogt R
• Description:
  This chapter will present some general background material on the cellular, biochemical, and genetic mechanisms of the immune system, then focus on specific examples that illustrate the promise and pitfalls of using immune biomarkers as tools for molecular epidemiologic research and public health practice. Some of the most exciting frontiers in medical science will be discussed: early detection of cancer through autoimmunity; malignancies that arise from the immune system itself; newborn screening for lethal immune deficiencies and latent autoimmune disorders; and neurodevelopmental disabilities that could result from maternal immune responses, which protect the mother but harm the fetus. The chapter concludes with some thoughts about current challenges and future directions. [Description provided by NIOSH]
• Subjects:
  Biochemistry Biomarkers Epidemiology Genetics Neoplasms Nervous System Nervous System Diseases Occupational Health Public Health Safety
• Keywords:
  Autoimmunity Cancer Cellular-function Cellular-structures Genetic-factors Immune-system Malignancy Molecular-biology Molecular-structure Neurological-diseases Neurological-system Public-health

  More +
• ISBN:
  9789283221630
• Publisher:
  International Agency for Research on Cancer
• Document Type:
  Text
• Genre:
  Book
• Place as Subject:
  Georgia ; Ohio ; OSHA Region 4 ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  EID - Education and Information Division
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  215-239
• NIOSHTIC Number:
  nn:20041096
• Citation:
  Molecular epidemiology: principles and practices. Rothman N, Hainaut P, Schulte P, Smith M, Boffetta P, Perera F, eds. Lyon, France: International Agency for Research on Cancer, IARC Scientific Publication, No 163, 2012 Jul; :215-239
• Editor(s):
  Rothman N; Hainaut P; Schulte P; Smith M; Boffetta P; Perera F
• Federal Fiscal Year:
  2012
• Peer Reviewed:
  False
• Source Full Name:
  Molecular epidemiology: principles and practices
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:511d15021b7c271fb41a660419ec92be9048f64c37daf80c3d81b2bcdf1859e7a40de55fbac3b1f1f56046771b3e4bcfcfcf42cb401a4e0b37cc9b9421f9766c
• Download URL:
  https://stacks.cdc.gov/view/cdc/193742/cdc_193742_DS1.pdf
• File Type:
  [PDF - 9.87 MB ]