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Revised Recommendation for an Occupational Exposure Standard for Benzene
  • Published Date:
    August 1976
  • Status:
Filetype[PDF - 475.22 KB]

  • Corporate Authors:
    National Institute for Occupational Safety and Health
  • Document Type:
  • Description:
    A revised recommendation for the NIOSH occupational exposure standard for benzene (71432) is reviewed. Previous recommendations and the relationships between benzene exposures and leukemia and other malignant diseases are discussed. The presence of benzene in gasoline and the hazards to workers exposed to benzene in printing, lithography, dry cleaning, and manufacturing industries are discussed. Epidemiological studies of benzene related diseases, and the relationship between benzene and blood abnormalities are considered along with studies of the mortality rates within the tire manufacturing, rubber, and petroleum refining and petroleum refining industries. Animal experiments associating leukemia with benzene exposure also are discussed. Data from various countries reporting fatalities resulting from benzene exposure is presented. The hypothesis that chemical carcinogens activate a latent leukemogenic virus in humans is explored. NIOSH concludes that benzene is leukemogenic and recommends that benzene be considered carcinogenic in man. NIOSH recommends an exposure standard of 1 part per million in samples of 1 liter of air per minute for 2 hours.

  • Supporting Files:
    No Additional Files