Physicochemical and toxicological properties of commercial carbon blacks modified by reaction with ozone

Details

• Personal Author:
  Dutta PK ; Nagy A ; Nash K ; Peebles BC ; Severance M ; Villamena FA ; Waldman WJ
• Description:
  Ozonation of two commercial carbon blacks (CBs), Printex 90 (P90) and Flammruss 101 (F101), was carried out and changes in their morphology, physical properties, and cytotoxicity were examined. The hypothesis examined was that different methods of manufacture of CBs influence their chemical reactivity and toxicological properties. Structural changes were examined by X-ray photoelectron spectroscopy, infrared spectroscopy, Raman spectroscopy, and electron paramagnetic resonance spectroscopy (EPR). Introduction of surface oxygen functionality upon ozonation led to changes in surface charge, aggregation characteristics, and free radical content of the CBs. However, these changes in surface functionality did not alter the cytotoxicity and release of inflammation markers upon exposure of the CBs to murine macrophages. Interaction of macrophages with F101 resulted in higher levels of inflammatory markers than P90, and the only structural correlation was with the higher persistent radical concentration on the F101. [Description provided by NIOSH]
• Subjects:
  Air Pollutants, Occupational Air Pollution, Indoor Chemistry Cytotoxins Dust Hazardous Substances Occupational Health Particulate Matter Safety
• Keywords:
  Air-contamination Airborne-dusts Airborne-particles Chemical-composition Cytotoxic-effects Cytotoxicity Models Pollutants Toxins
• ISSN:
  0013-936X
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  Ohio ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  45
• Issue:
  24
• NIOSHTIC Number:
  nn:20040639
• Citation:
  Environ Sci Technol 2011 Dec; 45(24):10668-10675
• Contact Point Address:
  Prabir K. Dutta, Department of Chemistry, The Ohio State University, 100 West 18th Avenue, Columbus, OH 43210
• Email:
  dutta@chemistry.ohio-state.edu
• CAS Registry Number:
  Aluminum silicate (CAS RN 1335-30-4) ; Carbon black (CAS RN 1333-86-4)
• Federal Fiscal Year:
  2012
• Performing Organization:
  The Ohio State University
• Peer Reviewed:
  True
• Start Date:
  20060801
• Source Full Name:
  Environmental Science and Technology
• End Date:
  20100731
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:df9d9dab59f2934774f06d2c80657f0601332e1e468a5da1fa11882be4474ad0ca637b4227aa6f3c1471028bd63c08042c302dbee206ab1098bca773a3c6c0de
• Download URL:
  https://stacks.cdc.gov/view/cdc/193430/cdc_193430_DS1.pdf
• File Type:
  [PDF - 953.48 KB ]