Parental occupational exposures and autism spectrum disorder

Details

• Personal Author:
  Burchfiel CM ; Charles LE ; Fekedulegn D ; Hertz-Picciotto I ; McCanlies EC ; Mnatsakanova A ; Sanderson, Wayne T.
• Description:
  Both self-report and industrial hygienist (IH) assessed parental occupational information were used in this pilot study in which 174 families (93 children with ASD and 81 unaffected children) enrolled in the Childhood Autism Risks from Genetics and Environment study participated. IH results indicated exposures to lacquer, varnish, and xylene occurred more often in the parents of children with ASD compared to the parents of unaffected children. Parents of children with ASD were more likely to report exposures to asphalt and solvents compared to parents of unaffected children. This study was limited by the small sample size, but results suggest that workplace exposures to some chemicals may be important in the etiology of ASD and deserve further investigation. [Description provided by NIOSH]
• Subjects:
  Behavior Environmental Monitoring Hydrocarbons Mental Disorders Mental Health Occupational Exposure Occupational Health Safety Solvents Xylenes
• Keywords:
  Asphalt-fumes Author Keywords: Autism Autism Spectrum Disorder Behavioral-disorders Children Developmental-disorders Employee-exposure Exposure Exposure-assessment Industrial-hygiene-programs Industrial-hygienists Mental-disorders Mental-processes Neuromotor-activity Occupation Parent Parental Exposures Sociological-factors Solvent-vapors Surveillance-programs

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• ISSN:
  0162-3257
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  California ; Kentucky ; OSHA Region 3 ; OSHA Region 4 ; OSHA Region 9 ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  HELD - Health Effects Laboratory Division
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  42
• Issue:
  11
• NIOSHTIC Number:
  nn:20040468
• Citation:
  J Autism Dev Disord 2012 Nov; 42(11):2323-2334
• Contact Point Address:
  Erin C. McCanlies, National Institute for Occupational Safety and Health, MS: L4050, 1095 Willowdale Rd., Morgantown, WV, 26505, USA
• Email:
  Eim4@cdc.gov
• CAS Registry Number:
  Asphalt (CAS RN 8052-42-4) ; Xylene (CAS RN 1330-20-7)
• Federal Fiscal Year:
  2013
• Peer Reviewed:
  True
• Source Full Name:
  Journal of Autism and Developmental Disorders
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:d207ca153be02d63f2642cb7fbfc361591403e7a86225c20fd41d2e55a8d6eabd6052a3d0491c17dceb229569c17e29247d087956de248cd3d72670315784096
• Download URL:
  https://stacks.cdc.gov/view/cdc/193310/cdc_193310_DS1.pdf
• File Type:
  [PDF - 351.55 KB ]