Hematological effects of long-term radiation exposure in Russian nuclear workers

Details

• Personal Author:
  Azizova TA ; Day RD ; Soaita AL
• Description:
  This book covers the following: radiation dose-response models, radiation effects at chromosomal and cellular level, radiosensitivity of the hematopoietic system, mayak product association, previous studies of long term occupational radiation exposure, sex related differences in radiosensitivity; Review of Repeated Measures Analysis Techniques: univariate analysis of variance (ANOVA), generalized linear models (GLM), linear mixed models, marginal model and GEE (generalized estimating equations), spline function, missing data, methodological overview - summary. OBJECTIVES AND SPECIFIC AIMS, METHODOLOGY, BACKGROUND, MAYAK PA WORKERS' EARLY CLINICAL EFFECT DATABASE: sampling procedures for MWECE database implementation, MWECE database format, study cohort. STUDY DESIGN: definition of study variables, descriptive analysis, statistical methods, missing data. RESULTS, DESCRIPTIVE ANALYSIS RESULTS: study cohort structure. MISSING DATA ASSESSMENT RESULTS: background, descriptive analysis of the missing data patterns, Missing Data Patterns and Mechanisms Assessment: drop-outs description, drop-outs mechanism assessment, mixed patterns missing data description, mixed patterns missing data assessment, Missing data analysis conclusion. STATISTICAL MODELING RESULTS: assessment of the coefficients in the models, assessment of goodness of fit of the models, numerical assessment of goodness of fit of the models, predicting the lymphocyte counts using the five models. [Description provided by NIOSH]
• Subjects:
  Accidents, Occupational Blood Chromosomes Diagnosis Environmental Monitoring Hematologic Diseases Hematologic Tests Occupational Exposure Occupational Health Radiation Radiation Dosimeters Safety Sex Characteristics

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• Keywords:
  Accidents Acute-exposure Acute-radiation-syndrome Biological-effects Blood-analysis Blood-cells Blood-disorders Cell-damage Cellular-function Chromosome-damage Clinical-diagnosis Clinical-symptoms Clinical-tests Dose-response Dosimetry Employee-exposure Exposure-assessment Hematology Hemodynamics Information-retrieval-systems Information-systems Injuries Ionizing-radiation Long-term-study Lymphocytes Mathematical-models Nuclear-hazards Nuclear-radiation Radiation-effects Radiation-monitoring Sampling Sex-factors Statistical-analysis Surveillance-programs

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• ISBN:
  9783836440004
• Publisher:
  VDM Verlag Dr. Mueller
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Book
• Place as Subject:
  OSHA Region 3 ; Pennsylvania
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  1-212
• NIOSHTIC Number:
  nn:20040321
• Citation:
  Soaita AL, Day RD, Azizova T, eds. Saarbrücken, Germany: VDM Verlag Dr. Mueller, 2008 Jan; :1-212
• Contact Point Address:
  Tamara V. Azizova, Southern Urals Biophysics Institute, 19 Ozyorskoe shosse, Ozyorsk, Chelyabinsk region, 456780, Russia
• Email:
  clinic@ozersk.com
• Editor(s):
  Soaita AL; Day RD; Azizova T
• Federal Fiscal Year:
  2008
• Performing Organization:
  University of Pittsburgh at Pittsburgh
• Peer Reviewed:
  False
• Start Date:
  20040901
• Source Full Name:
  Hematological effects of long-term radiation exposure in Russian nuclear workers
• End Date:
  20080630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:892afdb7eda85c3f32ca0815672365bec8bed766199a2072334e684a6bb154565809fb4acfa5544aaf20d5efe59af9f3d89bb37bfbaa41c19294b6795d5eb317
• Download URL:
  https://stacks.cdc.gov/view/cdc/193246/cdc_193246_DS1.pdf
• File Type:
  [PDF - 497.50 KB ]