Predictability of acute radiation injury severity

Details

• Personal Author:
  Azizova TV ; Day RD ; Druzhinina MB ; Kuniak M ; Okladnikova ND ; Osovets SV ; Pesternikova VS ; Schall LC ; Slaughter DM ; Sumina MV ; Teplyakov II ; Vasilenko EK ; Wald N ; Zhang A
• Description:
  Results of dose-response analyses for different clinical symptoms of acute radiation syndrome (ARS) are reported here. The analyses were performed on dosimetric and clinical data from a group of ARS patients (59 cases) exposed to gamma and neutron or gamma radiation alone due to nuclear accidents at Mayak Production Association (Mayak PA). Findings suggested the possibility of prediction of injury severity within the first hours or days after acute exposure based on clinical symptoms and signs such as the onset of vomiting, neutrophil count abnormalities in the peripheral blood within the first 2-3 hours after acute exposure, and lymphocyte count abnormalities in the peripheral blood within the first 24-48 h after acute exposure. [Description provided by NIOSH]
• Subjects:
  Accidents, Occupational Diagnosis Occupational Exposure Occupational Health Radiation Radiation Dosimeters Safety
• Keywords:
  Accidents Acute-exposure Acute-radiation-syndrome Author Keywords: Accidents Biological-effects Clinical-diagnosis Clinical-symptoms Clinical-tests Dose-response Dose Assessment Dosimetry Employee-exposure Exposure Health Effects Injuries Ionizing-radiation Nuclear Nuclear-hazards Nuclear-radiation Radiation-effects Radiation-monitoring Surveillance-programs

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• ISSN:
  0017-9078
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  California ; OSHA Region 3 ; OSHA Region 9 ; Pennsylvania
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  255-263
• Volume:
  94
• Issue:
  3
• NIOSHTIC Number:
  nn:20040320
• Citation:
  Health Phys 2008 Mar; 94(3):255-263
• Contact Point Address:
  Tamara V. Azizova, Southern Urals Biophysics Institute, 19 Ozyorskoe shosse, Ozyorsk, Chelyabinsk region, 456780, Russia
• Email:
  clinic@ozersk.com
• Federal Fiscal Year:
  2008
• Performing Organization:
  University of Pittsburgh at Pittsburgh
• Peer Reviewed:
  True
• Start Date:
  20040901
• Source Full Name:
  Health Physics
• End Date:
  20080630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:c31c7e08f76aa0fe1232d0ed096b43f46f20f927213fc57a7f086181ba0f3813b09389e6a01a42dfe4f3400d6cb60fc5b3608cdaafea6ffac5eda75ce45f9279
• Download URL:
  https://stacks.cdc.gov/view/cdc/193245/cdc_193245_DS1.pdf
• File Type:
  [PDF - 449.20 KB ]