Measuring surface area of airborne titanium dioxide powder agglomerates: relationships between gas adsorption, diffusion and mobility-based methods

Details

• Personal Author:
  Chen BT ; Cumpston JL ; Frazer DG ; Ku BK ; LeBouf, Ryan F. ; Stefaniak, Aleksandr B.
• Description:
  Inhalation toxicology studies generally use the Brunauer, Emmett, and Teller (BET) gas adsorption method to measure total surface area of particles whereas occupational exposures are more readily measured by real-time mobility-based surface areas or active surface area measured with diffusion charger-based instruments. Three surface area measurement methods were studied: filter-based inert gas adsorption (BET method), diffusion charging, and mobility-based methods. The goal of the project was to investigate and develop a correlation between the measurement methods. The experimental design consisted of measuring surface area in a series of five trials for each of two powder types, fine and ultrafine titanium dioxide with primary particle sizes of 440 and 20 nm, respectively, and two aerosol concentrations. Diffusion charger instruments tended to underestimate the total particle surface area measured by the BET, but were well correlated with mobility-based surface areas obtained from a scanning mobility particle sizer. Filter-based gas adsorption methods and diffusion charging methods provide different but valuable information on total and active surface areas of particles, respectively. Results indicate they should not be used as predictors of one another. [Description provided by NIOSH]
• Subjects:
  Hazardous Substances Inhalation Exposure Occupational Health Particulate Matter Safety
• Keywords:
  Analytical-instruments Analytical-methods Analytical-processes Author Keywords: Ultrafine Titanium Dioxide BET Diffusion-analysis Diffusion Charger Dioxides EHS Gas-adsorption Inhalants Measurement-equipment Nanotechnology Occupational Health Effects Particulates Surface-properties Surface Area Toxic-materials

  More +
• ISSN:
  1388-0764
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  Ohio ; OSHA Region 3 ; OSHA Region 5 ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DRDS - Division of Respiratory Disease Studies ; DART - Division of Applied Research and Technology ; HELD - Health Effects Laboratory Division
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  13
• Issue:
  12
• NIOSHTIC Number:
  nn:20040201
• Citation:
  J Nanopart Res 2011 Dec; 13(12):7029-7039
• Contact Point Address:
  A. B. Stefaniak, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Morgantown, WV 26505, USA
• Email:
  astefaniak@cdc.gov
• CAS Registry Number:
  Titania (CAS RN 13463-67-7)
• Federal Fiscal Year:
  2012
• Peer Reviewed:
  True
• Source Full Name:
  Journal of Nanoparticle Research
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:4c371d1627ff7f6f4a580748643e087416bd16e3886799925d9d9568b6cbb9ac17fa2e59eaeb22e4a0152d7a9bf1b8658e0782ec9796b82170ac4f587fb695f3
• Download URL:
  https://stacks.cdc.gov/view/cdc/193150/cdc_193150_DS1.pdf
• File Type:
  [PDF - 554.58 KB ]