Cause-specific mortality among a cohort of U.S. flight attendants

Details

• Personal Author:
  Grajewski, Barbara A. ; Hein, Misty J. ; Pinkerton LE ; Schubauer-Berigan, Mary K. ; Waters MA ; Zivkovich Z
• Description:
  Background: We evaluated mortality among 11,311 former U.S. flight attendants. The primary a priori outcomes of interest were breast cancer and melanoma. Methods: Vital status was ascertained through 2007, and life table analyses was conducted. Cumulative exposure to cosmic radiation and circadian rhythm disruption were estimated from work history data and historical published flight schedules. Results: All-cause mortality was less than expected among women but was elevated among men, primarily due to elevated HIV-related disease mortality. Mortality from breast cancer among women and melanoma was neither significantly elevated nor related to metrics of exposure. Mortality was elevated for non-Hodgkin's lymphoma among men; for alcoholism, drowning, and intentional self-harm among women; and for railway, water, and air transportation accidents. Conclusions: We found no evidence of increased breast cancer or melanoma mortality. Limitations include reliance on mortality data and limited power resulting from few melanoma deaths and relatively short employment durations. [Description provided by NIOSH]
• Subjects:
  Aircraft Circadian Rhythm Men Mortality Neoplasms Occupational Health Radiation Risk Assessment Safety Shift Work Schedule Skin Skin Diseases Sleep Sleep Initiation And Maintenance Disorders Women Workplace

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• Keywords:
  Aircrews Author Keywords: Flight Attendants Biological-effects Biological-monitoring Biostatistics Breast-cancer Cancer Cancer-rates Circadian-rhythms Circadian Rhythm Disruption Cohort Cosmic Radiation Flight-personnel Mortality Mortality-data Mortality-rates Mortality-surveys Quantitative-analysis Radiation-effects Radiation-exposure Risk-analysis Shift-workers Skin-cancer Skin-exposure Sleep-deprivation Statistical-analysis Work-environment Worker-health Workplace-studies

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• ISSN:
  0271-3586
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  Ohio ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DSHEFS - Division of Surveillance, Hazard Evaluations, and Field Studies ; DART - Division of Applied Research and Technology
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  25-36
• Volume:
  55
• Issue:
  1
• NIOSHTIC Number:
  nn:20039804
• Citation:
  Am J Ind Med 2012 Jan; 55(1):25-36
• Contact Point Address:
  Lynne E. Pinkerton, MDMPH, Industrywide Studies Branch, Division of Surveillance, Hazard Evaluations and Field Studies, National Institute for Occupational Safety and Health, 4676 Columbia Parkway, R-15, Cincinnati, OH 45226
• Email:
  lpinkerton@cdc.gov
• Federal Fiscal Year:
  2012
• NORA Priority Area:
  Transportation, Warehousing and Utilities ; Manufacturing
• Peer Reviewed:
  True
• Source Full Name:
  American Journal of Industrial Medicine
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:9e5a706333a371ecde40448e176c6843e74d936ec5d7cd17306c269ca3188e6062600a1b3937e4a847cfb675f7a62a5f84f71937891b545b569d172cb9a211ae
• Download URL:
  https://stacks.cdc.gov/view/cdc/192898/cdc_192898_DS1.pdf
• File Type:
  [PDF - 136.44 KB ]