Silicosis mortality with respiratory tuberculosis in the United States, 1968-2006

Details

• Personal Author:
  Bang KM ; Kreiss, Kathleen ; Mazurek JM ; Nasrullah M ; Wood JM
• Description:
  The presence of tuberculosis (TB) in patients with silicosis increases mortality risk. To characterize silicosis-respiratory TB comortality in the United States, the authors used 1968-2006 National Center for Health Statistics multiple cause-of-death data for decedents aged greater than or equal to 25 years. The authors calculated proportionate mortality ratios (PMRs) using available information on decedents' industries and occupations reported from 26 states from 1985 through 1999. Among 16,648 silicosis deaths, 2,278 (13.7 percent) had respiratory TB listed on the death certificate. Of silicosis-respiratory TB deaths, 1,666 decedents (73.1 percent) were aged greater than or equal to 65 years, 2,255 (99.0 percent) were male, and 1,893 (83.1 percent were white. Silicosis-respiratory TB deaths declined 99.5 percent during the study period (P less than 0.001 for time-related trend), from 239.8 per year during 1968-1972 to 1.2 per year during 2002-2006, with no reported deaths in 2006. Silicosis-respiratory TB deaths reported from Pennsylvania (n = 525; 1.29 per million population), Ohio (n = 258; 0.81 per million), and West Virginia (n = 146; 2.35 per million) accounted for 40.8 percent of all such deaths in the United States. The highest PMR for silicosis-respiratory TB death was associated with the "miscellaneous nonmetallic mineral and stone products" industry (PMR = 73.7, 95 percent confidence interval: 33.8, 139.8). In the United States, 2006 marked the first year since 1968 with no silicosis-respiratory TB deaths. The substantial decline in silicosis-respiratory TB comortality probably reflects prevention and control measures for both diseases. [Description provided by NIOSH]
• Subjects:
  Aging Epidemiology Lung Diseases Mortality Occupational Health Respiratory Tract Diseases Risk Assessment Risk Factors Safety Silicon Dioxide Silicosis

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• Keywords:
  Age-groups Author Keywords: Industry Information-retrieval-systems Lung-disease Mortality Mortality-data Mortality-rates Occupational Exposure Occupations Pulmonary-system-disorders Respiratory-system-disorders Risk-factors Silica-dusts Statistical-analysis Surveillance-programs Tuberculosis

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• ISSN:
  0002-9262
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  Georgia ; OSHA Region 3 ; OSHA Region 4 ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DRDS - Division of Respiratory Disease Studies
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  174
• Issue:
  7
• NIOSHTIC Number:
  nn:20039784
• Citation:
  Am J Epidemiol 2011 Oct; 174(7):839-848
• Contact Point Address:
  M. Nasrullah, Centers for Disease Control and Prevention, Division of HIV AIDS Prevention, Epidemic Intelligence Service, 1600 Clifton Road NE, Mailstop E46, Atlanta, GA 30333
• Email:
  snasrullah@cdc.gov
• CAS Registry Number:
  Quartz (SiO2) (CAS RN 14808-60-7) ; Silica (CAS RN 7631-86-9)
• Federal Fiscal Year:
  2012
• Peer Reviewed:
  True
• Source Full Name:
  American Journal of Epidemiology
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:8899d8d62a1baedf6c43fbd30b7655578609319348bb2ae4e55ba7d6f53f9dd43c91bdda4b698624f9a3b16a9b976484e64a7c946e0d6b2ff0bd762ec08ec6a3
• Download URL:
  https://stacks.cdc.gov/view/cdc/192886/cdc_192886_DS1.pdf
• File Type:
  [PDF - 212.46 KB ]