Separation of polybrominated diphenyl ethers, polychlorinated biphenyls, polychlorinated dibenzo-p-dioxins and dibenzo-furans in environmental samples using silica gel and florisil fractionation chromatography

Details

• Personal Author:
  Cai Z ; Jiang G ; Li A ; Liu H ; Wang Y ; Zhang Q
• Description:
  A comprehensive procedure was established for the fractionation of solvent-extracted environmental samples into three fractions containing polybrominated diphenyl ethers (PBDEs), polychlorinated biphenyls (PCBs) and polychlorinated dibenzo-p-dioxins and dibenzo-furans (PCDD/Fs), respectively. The procedure includes multi-layer silica gel chromatography to separate PBDEs from PCBs and PCDD/Fs, and subsequent separation of PCBs from PCDD/Fs using a florisil column. The numbers of congeners involved were 16, 19, and 17, for PBDEs, PCBs, and PCDD/Fs, respectively. The separation of the three chemical groups overcomes the potential mutual interferences, which are difficult to avoid even by the use of high resolution mass spectrometer (HRMS). In addition, this procedure efficiently eliminates most interfering substances from sample matrices for the subsequent instrumental analyses. The method was validated using mixed chemical standards, and applied for the analysis of environmental samples including sediment, sewage sludge and fish tissue. All the recoveries are within the acceptable ranges specified in the USEPA standard methods. [Description provided by NIOSH]
• Subjects:
  Chemistry Ether Occupational Health Polychlorinated Biphenyls Safety
• Keywords:
  Analytical-methods Analytical-processes Author Keywords: PBDEs Chemical-properties Ethers Florisil HRGC/HRMS PCBs PCDD/Fs Polychlorinated-biphenyls Sampling Sampling-methods Silica Gel Chromatography

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• ISSN:
  0003-2670
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  Illinois ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  314-320
• Volume:
  557
• Issue:
  1
• NIOSHTIC Number:
  nn:20039069
• Citation:
  Anal Chim Acta 2006 Jan; 557(1-2):314-320
• Contact Point Address:
  Guibin Jiang, State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, PR China
• Email:
  gbjiang@mail.rcees.ac.cn
• CAS Registry Number:
  1,1′-Biphenyl, chloro derivs. (CAS RN 1336-36-3)
• Federal Fiscal Year:
  2006
• Performing Organization:
  University of Illinois at Chicago
• Peer Reviewed:
  True
• Start Date:
  20050701
• Source Full Name:
  Analytica Chimica Acta
• End Date:
  20290630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:abc4561b1c04c44515d721cf23434a5b11931bd4b1a46d9dd2b4162199ae2f7248e5665fdeb3e4a62b2d656fb48f90fa6d9a574c1ca18b333c159b35aae37fb7
• Download URL:
  https://stacks.cdc.gov/view/cdc/192557/cdc_192557_DS1.pdf
• File Type:
  [PDF - 423.18 KB ]