Susceptibility of the aging lung to environmental injury

Details

• Personal Author:
  Green FHY ; Pinkerton KE ; Smiley-Jewell SM ; Wang L
• Description:
  With an ever-increasing number of elderly individuals in the world, a better understanding of the issues associated with aging and the environment is needed. The respiratory system is one of the primary interfaces between the body and the external environment. An expanding number of studies suggest that the aging pulmonary system (>65 years) is at increased risk for adverse health effects from environmental insult, such as by air pollutants, infection, and climate change. However, the mechanism(s) for increased susceptibility in this subpopulation are not well understood. In this review, we provide a limited but comprehensive overview of how the lung ages, examples of environmental exposures associated with injury to the aging lung, and potential mechanisms underlying the increased vulnerability of the aging lung to injury from environmental factors. [Description provided by NIOSH]
• Subjects:
  Aging Air Pollutants, Occupational Environmental Exposure Environmental Pollution Lung Occupational Health Respiratory System Respiratory Tract Diseases Safety
• Keywords:
  Air Contamination Author Keywords: Aging Lung Susceptibility Environmental Exposure Environmental Injury Environmental Pollution Lung Function Respiratory System Disorders
• ISSN:
  1069-3424
• Document Type:
  Text
• Funding:
  Cooperative Agreement
• Genre:
  Journal Article
• Place as Subject:
  California ; OSHA Region 9
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  31
• Issue:
  5
• NIOSHTIC Number:
  nn:20038355
• Citation:
  Semin Respir Crit Care Med 2010 Oct; 31(5):539-553
• Contact Point Address:
  Center for Health and the Environment, University of California at Davis, Davis, California
• Federal Fiscal Year:
  2011
• NORA Priority Area:
  Agriculture, Forestry and Fishing
• Performing Organization:
  University of California - Davis
• Peer Reviewed:
  True
• Start Date:
  20010930
• Source Full Name:
  Seminars in Respiratory and Critical Care Medicine
• End Date:
  20270929
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:f98f0a3cf124d9b14a222f79055f14331fda244b2a212362487e559a70d254a579105507c9799b4512efb9de5e22c33ea8de7101f9cc62bc907a9b9da36eb2a7
• Download URL:
  https://stacks.cdc.gov/view/cdc/192090/cdc_192090_DS1.pdf
• File Type:
  [PDF - 299.91 KB ]