Results of spirometry among individuals in a silicosis registry

Details

• Personal Author:
  Gardiner J ; Reilly MJ ; Rosenman, Kenneth D.
• Description:
  Objective: To determine whether individuals with simple silicosis have obstructive and restrictive decrements. Methods: The prevalence of spirometric abnormalities by radiograph profusion, smoking, duration, and latency from first silica exposure was evaluated among confirmed silicotics. Results: Among 526 silicotics, 17.3% who had never smoked and 26.5% of smokers had obstruction, 30.1% and 28.1% had restriction, and 22.4% and 25.7% had a mixed obstructive and restrictive pattern. Individuals with category 3 profusion or progressive massive fibrosis were more likely to have abnormalities. Conclusion: Both obstructive and restrictive patterns were observed regardless of smoking status with a low profusion category of simple silicosis. There was an increased prevalence of restrictive changes with increased profusion. After controlling for age, smoking, and duration of exposure to silica, there was a statistically significant increased risk of obstructive and mixed changes with progressive massive fibrosis. [Description provided by NIOSH]
• Subjects:
  Demography Epidemiology Irritants Lung Lung Diseases Occupational Health Respiratory Function Tests Respiratory System Respiratory Tract Diseases Safety Smokers

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• Keywords:
  Demographic-characteristics Lung-disease Lung-fibrosis Pulmonary-disorders Pulmonary-function-tests Pulmonary-system-disorders Respiratory-function-tests Respiratory-irritants Respiratory-system-disorders Silicosis Smoking Spirometry Statistical-analysis

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• ISSN:
  1076-2752
• Document Type:
  Text
• Funding:
  Cooperative Agreement
• Genre:
  Journal Article
• Place as Subject:
  Michigan ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  52
• Issue:
  12
• NIOSHTIC Number:
  nn:20038147
• Citation:
  J Occup Environ Med 2010 Dec; 52(12):1173-1178
• Contact Point Address:
  Kenneth D. Rosenman, MD, Professor of Medicine, Michigan State University, 117 West Fee, East Lansing, MI 48824
• Email:
  Rosenman@msu.edu
• CAS Registry Number:
  Quartz (SiO2) (CAS RN 14808-60-7)
• Federal Fiscal Year:
  2011
• Performing Organization:
  Michigan State University
• Peer Reviewed:
  True
• Start Date:
  20050701
• Source Full Name:
  Journal of Occupational and Environmental Medicine
• End Date:
  20260630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:4ca21a05a9d2b97609c3622bcae872fe72cf44629bc280a0aa80971e4cb4ea72ef163d8b2236a8ecf0fcda478526fce868de49db8bf6a174a168cd37fd8cfc34
• Download URL:
  https://stacks.cdc.gov/view/cdc/191945/cdc_191945_DS1.pdf
• File Type:
  [PDF - 114.17 KB ]