Modeling Dermal Exposure–an Illustration for Spray Painting Applications

Details

• Personal Author:
  Fent K ; Flynn MR ; Koto Y ; Nylander-French LA
• Description:
  This article presents a conceptual, mathematical model of dermal exposure resulting from aerosol deposition on human forearm hair. The model is applicable to exposure scenarios where dermal deposition is governed by aerosol impaction, interception, and diffusion mechanisms. The model employs filtration theory, single fiber efficiency equations, and a modified potential airflow approximation. The results are extended, using previously published results, for application to dermal deposition on the forearm during spray painting. The average (N = 8) predicted dermal deposition of 1,6-hexamethylene diisocyanate as collected on a 10-cm(2) tape strip is 108.9 (+/- 70.3) pmol, whereas field measurements indicated an average of 168.6 (+/- 82.0) pmol per strip. The corresponding measured average dermal flux was 3.63 pg/cm(2)s (+/- 1.34); the prediction was 2.24 pg/cm(2)sec (+/- 1.25). The study calls attention to the importance of body hair both for modeling and measuring dermal exposures. [Description provided by NIOSH]
• Subjects:
  Coal Coal Mining Engineering Geology Mining Occupational Health Safety
• Keywords:
  Aerosol-particles Aerosols Air-flow Automotive-industry Cyanates Environmental-health-monitoring Exposure-assessment Exposure-levels Isocyanates Mathematical-models Models Occupational-exposure Paint-spraying Painting Paints Pollutants Spray-painting

  More +
• ISSN:
  1545-9624
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  North Carolina ; OSHA Region 4
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  475-480
• Volume:
  3
• Issue:
  9
• NIOSHTIC Number:
  nn:20031380
• Citation:
  J Occup Environ Hyg 2006 Sep; 3(9):475-480
• Email:
  mflynn@email.unc.edu
• Federal Fiscal Year:
  2006
• Performing Organization:
  University of North Carolina, Chapel Hill, North Carolina
• Peer Reviewed:
  True
• Start Date:
  20030801
• Source Full Name:
  Journal of Occupational and Environmental Hygiene
• End Date:
  20070731
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:8ac1cf3cd57eed3ef61dddde2060991cffdc01f9851a7c060117072fa0fd0a4ec5883e823d4d3fd1b70948629b86a4d64c94c73bb5de12b1873e9442f05af338
• Download URL:
  https://stacks.cdc.gov/view/cdc/191640/cdc_191640_DS1.pdf
• File Type:
  [PDF - 290.57 KB ]