Whole Genome Sequencing of an Unusual Serotype of Shiga Toxin-producing Escherichia coli
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English
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Journal Article:Emerging Infectious Diseases
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Description:Shiga toxin-producing Escherichia coli serotype O117:K1:H7 is a cause of persistent diarrhea in travelers to tropical locations. Whole genome sequencing identified genetic mechanisms involved in the pathoadaptive phenotype. Sequencing also identified toxin and putative adherence genes flanked by sequences indicating horizontal gene transfer from Shigella dysenteriae and Salmonella spp., respectively.
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Subjects:
- Dispatch
- Escherichia coli
- Shiga toxin-producing Escherichia coli
- bacteria
- pathogenicity
- whole genome sequencing
- gene transfer
- serotype
- O117:K1:H7
- Genome, Bacterial
- High-Throughput Nucleotide Sequencing
- Humans
- Likelihood Functions
- Multilocus Sequence Typing
- Phylogeny
- Polymorphism, Single Nucleotide
- Serotyping
- Shiga-Toxigenic Escherichia coli
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ISSN:1080-6059 (online) ; 1080-6040 (print)
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Rights:Open Access
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Volume:19
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Issue:8
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Main Document Checksum:urn:sha-512:5b737029acae0efa60460dec3c2d7635f7f54f77bc3b1ee86e7e11c2c807427a7427e16686f1ff0b895eb6f0790d75ee16cb4c23806259aa1e642459868a60fc
Supporting Files
File Language:
English
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Emerging Infectious Diseases