On Predicting Multi-Route and Multimedia Residential Exposure to Chlorpyrifos and Diazinon

Details

• Personal Author:
  Ari H ; Gordon S ; Karuchit S ; Kim Y ; Lebowitz MD ; Moschandreas DJ ; O'Rourke MK ; Robertson G
• Description:
  This paper formulates regression models and examines their ability to associate exposures to chlorpyrifos and diazinon in residences with information obtained from questionnaires and environmental sampling of the National Human Exposure Assessment Survey Arizona (NHEXAS-AZ) database. A knowledge-based list of 29 potential exposure determinants was assembled from information obtained from six questionnaires administered in the course of the study. This list was used to select the independent variables of each model statistically and electronically. Depending on the data type of dependent and independent variables, four classes of regression models were developed to determine desired associations. Route-specific exposures were estimated using the indirect method of exposure estimation and measurements from the NHEXAS-AZ field study. The stepwise procedure was used to construct regression models. Significance level at P=0.10 was used for entry and retention of independent variables in a model. Twelve significant regression models were formulated to quantify associations among exposures and other variables in the NHEXAS-AZ database. Route-specific exposures to pesticides associate significantly with questionnaire-based variables such as preparation of pesticides, use of pesticide inside the house, and income level; and with concentration variables in three media: dermal wipe, sill wipe, and indoor air. Models formulated in this study may be used to estimate exposures to each of the pesticides. Yet, the use of these models must incorporate clear statements of the assumptions made in the formulation as well as the coefficient of determination and the confidence and prediction intervals of the dependent variable. [Description provided by NIOSH]
• Subjects:
  Air Pollution Air Pollution, Indoor Environmental Exposure Environmental Monitoring Epidemiology Insecticides Occupational Health Safety Surveys And Questionnaires
• Keywords:
  Air-quality Air-quality-monitoring Environmental-exposure Exposure-assessment Models Pesticides Pollution Questionnaires
• ISSN:
  1053-4245
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  Arizona ; Illinois ; Nevada ; Ohio ; OSHA Region 5 ; OSHA Region 9
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  56-65
• Volume:
  11
• Issue:
  1
• NIOSHTIC Number:
  nn:20031185
• Citation:
  J Expo Anal Environ Epidemiol 2001 Jan-Feb; 11(1):56-65
• Contact Point Address:
  D. J. Moschandreas, Department of Chemical and Environmental Engineering, Illinois Institute of Technology, Perlstein Hall, Room 127, 10 West 33rd St., Chicago, IL 60616
• Email:
  djm@iit.edu
• CAS Registry Number:
  Chlorpyrifos (CAS RN 2921-88-2) ; Diazinon (CAS RN 333-41-5)
• Federal Fiscal Year:
  2001
• Performing Organization:
  University of Arizona, Tucson, Arizona
• Peer Reviewed:
  True
• Start Date:
  19950701
• Source Full Name:
  Journal of Exposure Analysis and Environmental Epidemiology
• End Date:
  20060630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:f9fc07dbb68444f6561c169eff615e72475d06227292f4d8cbdfedeccd4a72654698fd7f546d7f4c5e8df73448aa91758bfbaf9b49e6950a93f75ed0c19d3815
• Download URL:
  https://stacks.cdc.gov/view/cdc/191510/cdc_191510_DS1.pdf
• File Type:
  [PDF - 125.67 KB ]