Use of Solid-Phase Microextraction to Detect and Quantify Gas-Phase Dicarbonyls in Indoor Environments

Details

• Personal Author:
  Ham JE ; Pacolay BD ; Wells JR
• Description:
  Solid-phase microextraction (SPME) was evaluated for the detection and quantification of the gas-phase dicarbonyls, glyoxal (GLY) and methylglyoxal (MGLY). Additionally, polydimethylsiloxane (PDMS), polydimethylsiloxane/divinylbenzene (PDMS/DVB), and carbowax/divinylbenzene (CW/DVB) fibers were tested to determine the optimum fiber for detection of these species. GLY and MGLY were derivatized with O-(2,3,4,5,6-pentafluorobenzyl)-hydroxylamine hydrochloride (PFBHA), extracted with SPME from headspace or bag chamber and then analyzed by GC/MS. The PDMS/DVB SPME fiber for on-fiber derivatization and subsequent sampling for gas-phase methylglyoxal provided the optimum combination of analytical reproducibility and sensitivity. Linearity of the calibration curve was achieved across a range of 11-222mug/m(3) (4-75ppb). [Description provided by NIOSH]
• Subjects:
  Air Pollution, Indoor Chemistry Chemistry, Analytic Chromatography Environmental Health Occupational Health Safety
• Keywords:
  Analytical-chemistry Analytical-processes Chromatographic-analysis Indoor-air-pollution Indoor-environmental-quality
• ISSN:
  0021-9673
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  OSHA Region 3 ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  HELD - Health Effects Laboratory Division
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  275-280
• Volume:
  1131
• Issue:
  1
• NIOSHTIC Number:
  nn:20031126
• Citation:
  J Chromatogr A 2006 Oct; 1131(1-2):275-280
• Contact Point Address:
  Exposure Assessment Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, 1095 Willowdale Road, Morgantown, WV 26505, USA
• Federal Fiscal Year:
  2007
• NORA Priority Area:
  Research Tools and Approaches: Exposure Assessment Methods
• Peer Reviewed:
  True
• Source Full Name:
  Journal of Chromatography A
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:47b5037ea24d62df894e00f355f05e6d11051e9901f715e54067a1a4d092e26323e38dd5916dcaa3a84641e1ae19e81b2aa066db80097039dbf9a97b39206a48
• Download URL:
  https://stacks.cdc.gov/view/cdc/191475/cdc_191475_DS1.pdf
• File Type:
  [PDF - 186.52 KB ]