NTP-CERHR Expert Panel Report on the Reproductive and Developmental Toxicity of Soy Formula

Details

• Personal Author:
  Bhatia J ; Calafat, Antonia M. ; Chambers C ; Culty M ; Etzel RA ; Flaws JA ; Hansen DK ; Hoyer PB ; Jeffery EH ; Kesner JS ; Marty S ; Rozman KK ; Thomas JA ; Umbach D
• Description:
  The National Toxicology Program (NTP) and the National Institute of Environmental Health Sciences (NIEHS) established the NTP Center for the Evaluation of Risks to Human Reproduction (CERHR) in June 1998. The purpose of the Center is to provide timely, unbiased, scientifically sound evaluations of human and experimental evidence for adverse effects on reproduction and development caused by agents to which humans may be exposed. Soy formula was selected for expert panel evaluation because of public concern for the possible health effects. Soy formula contains soy protein isolates and is fed to infants as a supplement to or replacement for human milk or cow milk. Soy protein isolates contain phytoestrogens that occur naturally in some legumes, especially soybeans. Phytoestrogens are non-steroidal, estrogenic compounds. In plants, nearly all phytoestrogens are bound to sugar molecules and these phytoestrogen-sugar complexes are not hormonally active. Phytoestrogens are found in many food products in addition to soy formula, especially soy-based foods such as tofu, soy milk, and in some over-the-counter dietary supplements. [Description provided by NIOSH]
• Subjects:
  Hazardous Substances Occupational Health Risk Assessment Risk Factors Safety Toxicology Urogenital System
• Keywords:
  Reproduction Reproductive-system Risk-analysis Risk-factors Toxic-effects Toxins
• ISSN:
  1542-9733
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  Arizona ; Arkansas ; California ; District of Columbia ; Georgia ; Illinois ; Indiana ; Kansas ; Maryland ; Michigan ; North Carolina ; Ohio ; OSHA Region 3 ; OSHA Region 4 ; OSHA Region 5 ; OSHA Region 6 ; OSHA Region 7 ; OSHA Region 9
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DART - Division of Applied Research and Technology
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  280-397
• Volume:
  77
• Issue:
  4
• NIOSHTIC Number:
  nn:20031046
• Citation:
  Birth Defects Res B Dev Reprod Toxicol 2006 Aug; 77(4):280-397
• Contact Point Address:
  Michael D. Shelby, PhD, NIEHS EC-32, PO Box 12233,Research Triangle Park, NC 27709
• Email:
  shelby@niehs.nih.gov
• Federal Fiscal Year:
  2006
• NORA Priority Area:
  Disease and Injury: Fertility and Pregnancy Abnormalities
• Peer Reviewed:
  True
• Source Full Name:
  Birth Defects Research Part B: Developmental and Reproductive Toxicology
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:9a55b4486c8c2a80f8cf6ca63e74bf79dde19141e600ae72dc10f0a21dd9cb7e113897175715a8e9b0e2e1f1508d82947d7b74024b3f34f90cbbce71cfa215ce
• Download URL:
  https://stacks.cdc.gov/view/cdc/191434/cdc_191434_DS1.pdf
• File Type:
  [PDF - 1.04 MB ]