Differences in Mortality by Radiation Monitoring Status in Portsmouth Naval Shipyard Workers

Details

• Personal Author:
  Daniels, Robert D. ; Schubauer-Berigan, Mary K. ; Silver S
• Description:
  Previous studies at the Portsmouth Naval Shipyard (PNS) yielded conflicting results for leukemia and lung cancer mortality. We examined standardized mortality and risk ratios (SMRs and SRRs) in an expanded cohort of PNS workers employed between January 1, 1952 and December 31, 1992 and followed through 1996. The all-cause SMR was 0.95 (95% confidence interval 0.93-0.96). SMRs were elevated with confidence intervals excluding 1.00 for lung cancer, esophageal cancer, and all cancers combined. Leukemia mortality was not elevated overall but exhibited a statistically significant positive linear trend with increasing cumulative external dose in SRR analyses. However, effects of solvent exposure could not be assessed at the cohort level. Several findings differed markedly by radiation monitoring status. Excess asbestosis deaths were limited to radiation workers, while several smoking-related causes of death had higher elevations among non-monitored workers. At PNS, asbestos exposure and possibly smoking, may be non-randomly distributed with respect to radiation exposure, suggesting potential for confounding in internal analyses of an occupational cohort. The effects of several potential confounders are being explored in nested lung cancer and leukemia case-control studies. [Description provided by NIOSH]
• Subjects:
  Asbestos Case Reports Inorganic Chemicals Lung Lung Diseases Mortality Neoplasms Occupational Exposure Occupational Health Radiation Respiratory System Respiratory Tract Diseases Risk Assessment Risk Factors Safety Ships

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• Keywords:
  Asbestosis Cancer Case-studies Lung-cancer Monitoring-systems Mortality-data Mortality-rates Occupational-exposure Occupational-health Radiation-effects Radiation-exposure Risk-analysis Risk-factors Shipyard-industry Shipyard-workers Shipyards Statistical-analysis

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• Publisher:
  American Public Health Association
• Document Type:
  Text
• Genre:
  Abstract or Summary ; Proceedings
• Place as Subject:
  Ohio ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DSHEFS - Division of Surveillance, Hazard Evaluations, and Field Studies
• Topic:
  Workplace Safety & Health
• Location:
  North America
• NIOSHTIC Number:
  nn:20030138
• Citation:
  APHA 132nd Annual Meeting and Exposition, Washington, DC, November 6-10, 2004. Washington, DC: American Public Health Association, 2004 Nov; :77054
• Contact Point Address:
  Health-Related Energy Research Branch, NIOSH, 5555 Ridge Ave, MS-R44, Cincinnati, OH 45213
• Email:
  zre4@cdc.gov
• Federal Fiscal Year:
  2005
• Peer Reviewed:
  False
• Source Full Name:
  APHA 132nd Annual Meeting of the American Public Health Association, November 6-10, 2004
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:546b9ead2d328f1bd299c50ad6b07f60fb29adb4082047669ee7281015f7e989bc68672e3d9d411a8d98b33c5049e88fc18ff448f2c85b7c11e5c9077a6daefe
• Download URL:
  https://stacks.cdc.gov/view/cdc/190954/cdc_190954_DS1.pdf
• File Type:
  [PDF - 69.54 KB ]