Cancer Incidence in a Cohort of Licensed Pesticide Applicators in Florida

Details

• Personal Author:
  Bean JA ; Fleming, Lora E. ; Hamilton K ; Rudolph M
• Description:
  This study is a standardized incidence ratio (SIR) analysis of cancer incidence of licensed pesticide applicators in Florida, compared with that of Florida's general population. Through extensive data linkages, 33,658 applicators were assembled who had 1266 incident cancers and 279,397 person-years from January 1, 1975, to December 31, 1993. Disease risk from ethanol and tobacco use were significantly decreased. Among males, prostate cancer (SIR = 1.91; 95% confidence interval [CI], 1.72-2.13) and testicular cancer (SIR = 2.48; 95% CI, 1.57-3.72) were significantly elevated. No confirmed cases of soft tissue sarcoma (STS) were found, and the incidence of non-Hodgkin's lymphoma was not increased. There were few female applicators; nevertheless, cervical cancer incidence (SIR = 3.69; 95% CI, 1.84-6.61) was significantly increased, while the incidence of breast cancer was significantly decreased. Cancers that have been associated with estrogen disrupters were found in male, but not female, pesticide applicators. The lack of soft tissue sarcoma is at odds with prior literature associated with the use of phenoxy herbicides. [Description provided by NIOSH]
• Subjects:
  Agriculture Insecticides Neoplasms Occupational Exposure Occupational Health Risk Assessment Risk Factors Safety
• Keywords:
  Agricultural-chemicals Cancer Cancer-rates Occupational-exposure Pesticide-residues Pesticides-and-agricultural-chemicals Risk-analysis Risk-factors Sarcomagenicity
• ISSN:
  1076-2752
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  Florida ; OSHA Region 4
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  279-288
• Volume:
  41
• Issue:
  4
• NIOSHTIC Number:
  nn:20029985
• Citation:
  J Occup Environ Med 1999 Apr; 41(4):279-288
• Contact Point Address:
  Lora E. Fleming, MD, PhD, MPH, MSc, Department of Epidemiology and Public Health, University of Miami School of Medicine, PO Box 016069 (R-669), Miami, FL 33101
• Federal Fiscal Year:
  1999
• Performing Organization:
  University of Miami, Miami, Florida
• Peer Reviewed:
  True
• Start Date:
  19921101
• Source Full Name:
  Journal of Occupational and Environmental Medicine
• End Date:
  19970331
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:993f665f5a6311928957ee6379e83abc3c07523b155948e0b3d6ea0777a54fa0e90c15c3f2a14b33c9fa9a1be534d700eabccac9f4b9211ed15407cfcd7f816f
• Download URL:
  https://stacks.cdc.gov/view/cdc/190848/cdc_190848_DS1.pdf
• File Type:
  [PDF - 574.97 KB ]