Petrochemical Exposure and Menstrual Disturbances

Details

• Personal Author:
  Carlson J ; Christiani, David C. ; Cui S ; Huang Y ; Ma G ; Ryan L ; Snow R ; Thurston SW ; Wang L ; Xu X ; You L ; Carlson J ; Christiani, David C. ; Cui S ; Huang Y ; Ma G ; Ryan L ; Snow R ; Thurston SW ; Wang L ; Xu X ; You L
• Description:
  BACKGROUND: An exploratory, cross-sectional retrospective study was conducted to examine the effects of benzene exposure on menstrual problems. METHODS: The study was based on a survey administered to over 3,000 women who worked in a large petrochemical company in Beijing, China. An abnormal menstrual cycle length (AMCL), defined as an average menstrual cycle length of greater than 35 days or less than 21 days, is the major outcome of interest. RESULTS: After 7 years of benzene exposure, the adjusted odds ratio of having AMCL for each additional 5 years of exposure was 1.71 (95% CI 1.27-2.31). Feeling stressed at work was also an important predictor. CONCLUSIONS: This study suggests a significant association of benzene exposure and perceived stress with menstrual disturbance. A prospective study is needed to confirm this finding. [Description provided by NIOSH]
• Subjects:
  Occupational Exposure Occupational Health Risk Assessment Risk Factors Safety Solvents Urogenital Diseases Urogenital System Women
• Keywords:
  Analytical Methods Chemical Hypersensitivity Exposure Assessment Humans Occupational Exposure Organic Solvents Reproductive System Disorders Risk Factors
• ISSN:
  0271-3586
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article ; Journal Article
• Place as Subject:
  Massachusetts ; OSHA Region 1
• CIO:
  National Institute for Occupational Safety and Health (NIOSH) ; National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health ; Workplace Safety & Health
• Location:
  North America ; North America
• Volume:
  38
• Issue:
  5
• NIOSHTIC Number:
  nn:20029931
• Citation:
  Am J Ind Med 2000 Nov; 38(5):555-564
• Contact Point Address:
  Sally W. Thurston, Department of Biostatistics, Harvard School of Public Health, 655 Huntington Ave., Boston, MA 02115
• Email:
  sthursto@hsph.harvard.edu
• CAS Registry Number:
  Ammonia (CAS RN 7664-41-7) ; Benzene (CAS RN 71-43-2) ; Hydrogen sulfide (CAS RN 7783-06-4) ; Manganese (CAS RN 7439-96-5) ; Ammonia (CAS RN 7664-41-7) ; Benzene (CAS RN 71-43-2) ; Hydrogen sulfide (CAS RN 7783-06-4) ; Manganese (CAS RN 7439-96-5)
• Federal Fiscal Year:
  2001
• NORA Priority Area:
  Disease and Injury: Fertility and Pregnancy Abnormalities ; Disease and Injury: Fertility and Pregnancy Abnormalities
• Performing Organization:
  Harvard University, Boston, Massachusetts
• Peer Reviewed:
  True
• Start Date:
  19921201
• Source Full Name:
  American Journal of Industrial Medicine
• End Date:
  19990131
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:1cd4ba7853d970bdc89c487ad516a698c83d3b0a87d60b8890329b80b182aa7bf49d11380983d78e307ee96c1a65861e3bdd892408dac90c2eba1eeb5182264e
• Download URL:
  https://stacks.cdc.gov/view/cdc/190809/cdc_190809_DS1.pdf
• File Type:
  [PDF - 127.34 KB ]