Conference Overview: Molecular Mechanisms of Metal Toxicity and Carcinogenesis

Details

• Personal Author:
  Bower JJ ; Leonard, Stephen S. ; Shi XL
• Description:
  Chronic exposure to many heavy metals and metal-derivatives is associated with an increased risk of cancer, although the mechanisms of tumorigenesis are largely unknown. Approximately 125 scientists attended the 3rd Conference on Molecular Mechanisms of Metal Toxicity and Carcinogenesis and presented the latest research concerning these mechanisms. Major areas of focus included exposure assessment and biomarker identification, roles of ROS and antioxidants in carcinogenesis, mechanisms of metal-induced DNA damage, metal signalling, and the development of animal models for use in metal toxicology studies. Here we highlight some of the research presented, and summarize the conference proceedings. [Description provided by NIOSH]
• Subjects:
  Animals Antioxidants Biomarkers Carcinogens DNA Environmental Monitoring Hazardous Substances Metals Neoplasms Occupational Health Risk Assessment Risk Factors Safety

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• Keywords:
  Animal-studies Author Keywords: Antioxidants Cancer Carcinogenesis Carcinogenicity DNA-damage DNA Damage Exposure-assessment Exposure-levels Reactive Oxygen Species Risk-analysis Risk-factors Toxic-effects Toxins Tumorigenesis Tumorigens

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• ISSN:
  0300-8177
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  OSHA Region 3 ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  HELD - Health Effects Laboratory Division
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  3-15
• Volume:
  279
• Issue:
  1
• NIOSHTIC Number:
  nn:20028926
• Citation:
  Mol Cell Biochem 2005 Nov; 279(1-2):3-15
• Federal Fiscal Year:
  2006
• Peer Reviewed:
  True
• Source Full Name:
  Molecular and Cellular Biochemistry
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:cfb0f359cc54aea3d5e94dccb457bf11007f81a5e8583dba5cfc3023b297f178f7b8d7a2c326c2d97f7934c484a903bde5064a7193163a6c9e17e0f664509bfa
• Download URL:
  https://stacks.cdc.gov/view/cdc/190016/cdc_190016_DS1.pdf
• File Type:
  [PDF - 166.86 KB ]