Survey of Sulfur-Containing Rubber Accelerator Levels in Latex and Nitrile Exam Gloves

Details

• Personal Author:
  Bledsoe TA ; Depree GJ ; Siegel, Paul D.
• Description:
  2-Mercaptobenzothiazole and zinc dialkyldithiocarbamates are commonly used sulfur-containing rubber vulcanization accelerators known to cause allergic contact dermatitis. Exposure to these agents occurs through clothing such as undergarments and shoes, latex medical devices and latex and nitrile gloves. A simple, inexpensive screening method for total sulfur accelerator and a high performance liquid chromatographic speciation method were developed in the present study. These methods were applied to screen and quantify the sulfur accelerator content from 38 brands of 'off-the-shelf' latex and nitrile gloves obtained from commercial vendors. It was found that accelerator levels ranged from not detectable to 7.35 mg/g in the gloves analysed. Brands were found to contain single and multiple accelerator species within the glove. Powdered gloves had significantly higher accelerator levels than powder-free gloves from the same manufacturer; however, these chemical accelerators do not preferentially partition to the powder. The present analytical methodology is suitable for both manufacturing quality validation purposes, as well as for accelerator allergy research. Description provided by NIOSH
• Subjects:
  • Dermatitis
  • Hypersensitivity
  • Nitriles
  • Occupational Exposure
  • Occupational Health
  • Personal Protective Equipment
  • Protective Clothing
  • Safety
  • Safety Management
  • Skin
  More +
• Keywords:
  • Gloves
  • Nitriles
  • Allergic-dermatitis
  • Contact-dermatitis
  • Dermatitis
  • Occupational-exposure
  • Allergic-reactions
  • Safety-research
  • Safety-measures
  • Safety-clothing
• ISSN:
  0105-1873
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  OSHA Region 3 ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  HELD - Health Effects Laboratory Division
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  107-113
• Volume:
  53
• Issue:
  2
• NIOSHTIC Number:
  nn:20027920
• Citation:
  Contact Dermatitis 2005 Aug; 53(2):107-113
• Contact Point Address:
  Paul D. Siegel, PhD, Allergy and Clinical Immunology Branch, M/S L4020, HELD/NIOSH, 1095 Willowdale Road, Morgantown WV 26505-2888, USA
• Email:
  PSiegel@cdc.gov
• CAS Registry Number:
  • 2-Mercaptobenzothiazole (CAS RN 149-30-4)
• Federal Fiscal Year:
  2005
• NORA Priority Area:
  Disease and Injury: Allergic and Irritant Dermatitis
• Peer Reviewed:
  True
• Source Full Name:
  Contact Dermatitis
• Download URL:
  https://stacks.cdc.gov/view/cdc/189675/cdc_189675_DS1.pdf
• File Type:
  [PDF - 694.24 KB]
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:b849c1b34367095afb7bc3c37f2ec23d58d65b6ae880238f06295508bc9884a09746f49a9c1d5e48b2a6d164f42fb4c745748aca8325000c4f688fc45206654a