Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Maini, Rishma ; Henderson, Katherine L. ; Sheridan, Elizabeth A. ; Lamagni, Theresa ; Nichols, Gordon ; ... More +
Maini, Rishma ; Henderson, Katherine L. ; Sheridan, Elizabeth A. ; Lamagni, Theresa ; Nichols, Gordon ; Delpech, Valerie ; Phin, Nick ; Less -
Description:
After an increase in the number of reported cases of Pneumocystis jirovecii pneumonia in England, we investigated data from 2000-2010 to verify the increase. We analyzed national databases for microbiological and clinical diagnoses of P. jirovecii pneumonia and associated deaths. We found that laboratory-confirmed cases in England had increased an average of 7% per year and that death certifications and hospital admissions also increased. Hospital admissions indicated increased P. jirovecii pneumonia diagnoses among patients not infected with HIV, particularly among those who had received a transplant or had a hematologic malignancy. A new risk was identified: preexisting lung disease. Infection rates among HIV-positive adults decreased. The results confirm that diagnoses of potentially preventable P. jirovecii pneumonia among persons outside the known risk group of persons with HIV infection have increased. This finding warrants further characterization of risk groups and a review of P. jirovecii pneumonia prevention strategies.
Subject:
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Adolescent
Adult
Aged
Aged, 80 And Over
Age Distribution
Child
Child, Preschool
England
Female
Fungi
Hematologic Neoplasms
Humans
Infant
Lung Diseases
Male
Middle Aged
P. Jirovecii Pneumonia
Pneumocystis Jirovecii
Pneumonia
Pneumonia, Pneumocystis
Research
Respiratory Infections
Sex Distribution
Surveillance
Young Adult

Source:
Emerg Infect Dis. 19(3):386-392. ;
Document Type:
Journal Article ;
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
[+]
urn:sha256:1086667377a0f2cf06dfaafb46709a69a9b992e51d4581d74fa301efee60280c
File Type:

Supporting Files

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