Kinetics and Reaction Products of Ozone and Surface-Bound Squalene

Details

• Personal Author:
  Coleman BK ; Morrison GC ; Wells JR
• Description:
  Because of the high occupant density in aircraft, the surface chemistry of ozone and squalene, an important component of skin oil, was evaluated. A reaction probability of (45+/-14)×10^-5 was determined for the reaction of squalene (2,6,10,15,19,23-hexamethyl-2,6,10,14,18,22-tetracosahexaene) with ozone (50 parts per billion (ppb)) on a glass plate surface using the Field and Laboratory Emission Cell (FLEC) Automation and Control System (FACS). To more clearly define part of squalene's indoor environment degradation mechanism, gas-phase and surface-bound products of the squalene+O3 reaction were also investigated. Emitted products were captured in solution, derivatized with O-(2,3,4,5,6-pentafluorobenzyl)hydroxylamine (PFBHA), and analyzed by gas chromatography and ion trap mass spectroscopy. The identified squalene+O3 reaction products were: 6-methyl-5-hepten-2-one (6MHO, ((CH3)2C=CH(CH2)2 C(=O)CH3)), glyoxal (ethanedial, HC(=O)C(=O)H), 4-oxopentanal (4OPA, CH3C(=O)CH2CH2 CH(=O)), and 6,10-dimethylundeca-5,9-dien-2-one (geranyl acetone). The compound 5,9,13-trimethyltetradeca-4,8,12-trienal is proposed as the other major squalene+O3 reaction product. This compound was determined from mass spectrometry coupled with plausible squalene+O3 reaction mechanisms based on previously published volatile organic compound+O3 gas-phase reaction mechanisms. [Description provided by NIOSH]
• Subjects:
  Aircraft Aldehydes Environmental Monitoring Formaldehyde Occupational Health Plastics Safety Skin Skin Absorption
• Keywords:
  Air-quality-monitoring Air-sampling-techniques Emission-sources Flight-personnel Flying Gas-detectors Humans Oils Organic-compounds Plastic-products Skin-absorption Skin-exposure

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• ISSN:
  1546-962X
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  California ; Missouri ; OSHA Region 3 ; OSHA Region 7 ; OSHA Region 9 ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  HELD - Health Effects Laboratory Division
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  5
• Issue:
  7
• NIOSHTIC Number:
  nn:20034280
• Citation:
  J ASTM Int 2008 Jul/Aug; 5(7):JAI101629
• CAS Registry Number:
  Ozone (CAS RN 10028-15-6)
• Federal Fiscal Year:
  2008
• NORA Priority Area:
  Services
• Peer Reviewed:
  True
• Source Full Name:
  Journal of ASTM International
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:cb2815573fda27a8229cd05f3c8c4a920381c4d31219228b76e7afa9ac4b39141f461d673e05fa3d3c8f9e7013baa7bbe3bc2a123defbd6e16fa181ac0b0c8a0
• Download URL:
  https://stacks.cdc.gov/view/cdc/189546/cdc_189546_DS1.pdf
• File Type:
  [PDF - 1.59 MB ]