Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Cabanel, Nicolas ; Leclercq, Alexandre ; Chenal-Francisque, Viviane ; Annajar, Badereddin ; Rajerison, Minoarisoa ; ... More +
Cabanel, Nicolas ; Leclercq, Alexandre ; Chenal-Francisque, Viviane ; Annajar, Badereddin ; Rajerison, Minoarisoa ; Bekkhoucha, Souad ; Bertherat, Eric ; Carniel, Elisabeth Less -
Description:
After 25 years of no cases of plague, this disease recurred near Tobruk, Libya, in 2009. An epidemiologic investigation identified 5 confirmed cases. We determined ribotypes, Not1 restriction profiles, and IS100 and IS1541 hybridization patterns of strains isolated during this outbreak. We also analyzed strains isolated during the 2003 plague epidemic in Algeria to determine whether there were epidemiologic links between the 2 events. Our results demonstrate unambiguously that neighboring but independent plague foci coexist in Algeria and Libya. They also indicate that these outbreaks were most likely caused by reactivation of organisms in local or regional foci believed to be dormant (Libya) or extinct (Algeria) for decades, rather than by recent importation of Yersinia pestis from distant foci. Environmental factors favorable for plague reemergence might exist in this area and lead to reactivation of organisms in other ancient foci.
Subjects:
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Adolescent Algeria Bacteria Child, Preschool Disease Outbreaks Female Humans Libya Male Oran Outbreak Phylogeny Plague Polymorphism, Restriction Fragment Length Reemergence Research Ribotyping Tobruk Yersinia Pestis Young Adult
Source:
Emerg Infect Dis. 19(2):230-236.
Document Type:
Journal Article
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
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urn:sha256:019e9ee52a263cd0594bfccf72372944a8bc06c55a0387b2e68334bc548ceb1d
Download URL:
https://stacks.cdc.gov/view/cdc/18945/cdc_18945_DS1.pdf
File Type:

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