Characteristics of Aerosols Generated During a Cough

Details

• Personal Author:
  Afshari AA ; Frazer DG ; Goldsmith WT ; Petsonk, Edward L. ; Philips N ; Weber KC
• Description:
  A system including a spirometer and LAS-X particle analyzer was designed to examine aerosols generated during a cough. The system was held at 37 degrees C in a temperature controlled chamber. Air was pulled through a HEPA filter and the spirometer at a constant rate (5 l/min) so that aerosols introduced to the spirometer-aerosol analyzer system were continuously washed out. A subject breathing ambient air coughed into the spirometer, then breathed HEPA filtered air and coughed at 2 min intervals for 6 min. Background aerosol measurements were recorded prior to each cough. Preliminary experiments showed that the difference in the number of particles recovered from the spirometer with respect to background (NPD) was greatest following the first cough, was reduced during the second cough, but tended to increase following the third and four1h coughs. Particle diameters ranged between 0.1 and 5.0 micro m after each cough, and more that 95% of the particles had diameters less than 1.0 micro m. Results also showed that there was a significant variation in NPD (+/-300%) between subjects following each of the four coughs. [Description provided by NIOSH]
• Subjects:
  Aerosols Lung Occupational Health Particulate Matter Respiratory Function Tests Respiratory System Safety
• Keywords:
  Aerosol-particles Breathing Inhalation-studies Lung-function Particle-counters Particulates Spirometry
• ISSN:
  0892-6638
• Document Type:
  Text
• Genre:
  Abstract or Summary ; Proceedings
• Place as Subject:
  OSHA Region 3 ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  HELD - Health Effects Laboratory Division ; DRDS - Division of Respiratory Disease Studies
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  11
• Issue:
  3
• NIOSHTIC Number:
  nn:20033993
• Citation:
  FASEB J 1997 Feb; 11(3):A348
• Federal Fiscal Year:
  1997
• Peer Reviewed:
  False
• Source Full Name:
  The FASEB Journal
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:8c2b44ff0daf01f996e7b1a064135b419dcc11f4c2d75c6daeafc3446deb7b54e659f7668f7340a6dbe416baac9fa8e2e5978e916655ce3edf4f66d4da749156
• Download URL:
  https://stacks.cdc.gov/view/cdc/189384/cdc_189384_DS1.pdf
• File Type:
  [PDF - 329.21 KB ]