Nipah Virus Infection Outbreak with Nosocomial and Corpse-to-Human Transmission, Bangladesh

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Sazzad, Hossain M.S. ; Hossain, M. Jahangir ; Gurley, Emily S. ; Ameen, Kazi M.H. ; Parveen, Shahana ; Islam, M. Saiful ; Faruque, Labib I. ; Podder, Goutam ; Banu, Sultana S. ; Lo, Michael K. ; Rollin, Pierre E. ; Rota, Paul A. ; Daszak, Peter ; Rahman, Mahmudur ; Luby, Stephen P.
• Description:
  Active Nipah virus encephalitis surveillance identified an encephalitis cluster and sporadic cases in Faridpur, Bangladesh, in January 2010. We identified 16 case-patients; 14 of these patients died. For 1 case-patient, the only known exposure was hugging a deceased patient with a probable case, while another case-patient's exposure involved preparing the same corpse for burial by removing oral secretions and anogenital excreta with a cloth and bare hands. Among 7 persons with confirmed sporadic cases, 6 died, including a physician who had physically examined encephalitis patients without gloves or a mask. Nipah virus-infected patients were more likely than community-based controls to report drinking raw date palm sap and to have had physical contact with an encephalitis patient (29% vs. 4%, matched odds ratio undefined). Efforts to prevent transmission should focus on reducing caregivers' exposure to infected patients' bodily secretions during care and traditional burial practices.
• Subjects:
  Adolescent Adult Arecaceae Beverages Burial Cadaver Case-Control Studies Child Child, Preschool Cross Infection Disease Outbreaks Encephalitis, Viral Epidemiological Monitoring Female Henipavirus Infections Humans Infectious Disease Transmission, Patient-to-Professional Male Middle Aged Nipah Virus Physicians Risk Factors Synopsis Young Adult

  More +
• Source:
  Emerg Infect Dis. 19(2):210-217.
• Document Type:
  Journal Article
• Funding:
  2R01-TW005869/TW/FIC NIH HHS/United States ; 5U01CI000628-01/CI/NCPDCID CDC HHS/United States ; R01 GM100471/GM/NIGMS NIH HHS/United States
• Place as Subject:
  Bangladesh
• Location:
  Asia
• Volume:
  19
• Issue:
  2
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:2b97bcc6f0da767b7b1808628dc54c23e86185cdd11f015d938dccf89642ed7f
• Download URL:
  https://stacks.cdc.gov/view/cdc/18932/cdc_18932_DS1.pdf
• File Type:
  [PDF - 881.25 KB ]