In Vitro Genotoxicity of Particulate and Semi-Volatile Organic Compound Exhaust Materials from a Set of Gasoline and a Set of Diesel Engine Vehicles Operated at 30 Degrees F

Details

• Personal Author:
  Ensell M ; Keane M ; Ong T ; Wallace W
• Description:
  Conclusions and Directions: 1. Diesel and gasoline engine exhaust particulate can contain genotoxic compounds. 2. DEP genotoxicant content is affected by fuel, engine operating condition. 3. DEP can express genotoxic activity in vitro under conditions modeling soot deposition in the lung. 4. Biologically-available genotoxicant activity of engine exhaust particulate can be assayed in short-term tests in a physiologically-plausible manner. 5. Correlation can be sought with fuel, engine design and operation parameters. 6. The help evaluate and guide the development of duels, engine design, and emission controls. [Description provided by NIOSH]
• Subjects:
  Aerosols Air Pollutants, Occupational Fuel Oils Occupational Health Particulate Matter Safety Vehicle Emissions
• Keywords:
  Aerosol-particles Airborne-particles Diesel-emissions Diesel-engines Diesel-exhausts Exhaust-gases Fuels Gene-mutation Genotoxic-effects Genotoxicity Particulates

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• Publisher:
  Department of Energy
• Document Type:
  Text
• Genre:
  Proceedings
• Place as Subject:
  District of Columbia ; OSHA Region 1 ; OSHA Region 3 ; Rhode Island ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  HELD - Health Effects Laboratory Division
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  1-58
• NIOSHTIC Number:
  nn:20033766
• Citation:
  Proceedings of the 9th Diesel Engine Emission Reduction (DEER) Conference, August 24-28, 2003, Newport, Rhode Island. Washington, DC: Department of Energy, 2003 Aug; :1-58
• Contact Point Address:
  William Wallace, National Institute for Occupational Safety and Health, 1095 Willowdale Rd., Morgantown, WV 26505
• Email:
  wwallace@cdc.gov
• Federal Fiscal Year:
  2003
• Peer Reviewed:
  False
• Source Full Name:
  Proceedings of the 9th Diesel Engine Emission Reduction (DEER) Conference, August 24-28, 2003, Newport, Rhode Island
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:4fb72b77bac30338d22f093e5e93f66e7d8d65f24d9aa967a23a00a5fd59d93622e0fffce2c7a9a86f03e027b95734ad14936d1c08db11b5c86b9c17d0c699f8
• Download URL:
  https://stacks.cdc.gov/view/cdc/189216/cdc_189216_DS1.pdf
• File Type:
  [PDF - 320.43 KB ]