Nontuberculous Mycobacterial Infection after Fractionated CO2 Laser Resurfacing
Published Date:Mar 2013
Source:Emerg Infect Dis. 19(3):365-370.
Drug Therapy, Combination
Fractionated CO2 Laser Resurfacing
Laser Therapy, Low-Level
Mycobacterium Infections, Nontuberculous
Nontuberculous Mycobacterial Infection
Skin Diseases, Bacterial
Tuberculosis And Other Mycobacteria
Description:Nontuberculous mycobacteria are increasingly associated with cutaneous infections after cosmetic procedures. Fractionated CO2 resurfacing, a widely used technique for photorejuvenation, has been associated with a more favorable side effect profile than alternative procedures. We describe 2 cases of nontuberculous mycobacterial infection after treatment with a fractionated CO2 laser at a private clinic. Densely distributed erythematous papules and pustules developed within the treated area within 2 weeks of the laser procedure. Diagnosis was confirmed by histologic analysis and culture. Both infections responded to a 4-month course of a multidrug regimen. An environmental investigation of the clinic was performed, but no source of infection was found. The case isolates differed from each other and from isolates obtained from the clinic, suggesting that the infection was acquired by postprocedure exposure. Papules and pustules after fractionated CO2 resurfacing should raise the suspicion of nontuberculous mycobacterial infection.
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