In Vivo Cyclical Joint Loading Decreases Unmineralized Cartilage Thickness in the Rabbit Metacarpophalangeal

Details

• Personal Author:
  King KB ; Opel C ; Rempel D
• Description:
  Understanding the mechanobiology of joint loading is essential for progress in treating osteoarthritis as well as other degenerative joint diseases and to help engineer cartilage tissue replacements. This study examines articular joint tissue changes resulting from in vivo cyclical loading in a rabbit model. This new animal model has the potential to advance our understanding of adult endochondral ossification and degenerative joint disease. [Description provided by NIOSH]
• Subjects:
  Animals Biomechanical Phenomena Cumulative Trauma Disorders Laboratories Musculoskeletal Diseases Musculoskeletal System Occupational Health Safety
• Keywords:
  Animal-studies Biomechanics Bone-disorders Cumulative-trauma Cumulative-trauma-disorders In-vivo-studies Injuries Laboratory-animals Models Muscles Musculoskeletal-system Musculoskeletal-system-disorders Repetitive-work

  More +
• ISSN:
  0149-6433
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Abstract or Summary ; Proceedings
• Place as Subject:
  California ; OSHA Region 9
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  51
• NIOSHTIC Number:
  nn:20033285
• Citation:
  Trans Annu Meet Orthop Res Soc 2005 Mar; 51:1638
• Contact Point Address:
  Department of Medicine, University of California, San Francisco, CA
• Email:
  kbking@itsa.ucsf.edu
• Federal Fiscal Year:
  2005
• NORA Priority Area:
  Disease and Injury: Musculoskeletal Disorders of the Upper Extremities
• Performing Organization:
  University of California - San Francisco
• Peer Reviewed:
  False
• Start Date:
  20010701
• Source Full Name:
  Transactions of the Annual Meeting of the Orthopaedic Research Society
• End Date:
  20060630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:c88401efe89ee34651cd47b03b714f5e730a4d489dfaf6e9f4040ed067dd36e4131c99ebe446d6fd161f9518449010d5c1b5541a72094d20870ed7f00b67aa45
• Download URL:
  https://stacks.cdc.gov/view/cdc/188927/cdc_188927_DS1.pdf
• File Type:
  [PDF - 15.67 KB ]