Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Couto de Mello, Karla Gripp ; Queiroz Mello, Fernanda C. ; Borga, Liamar ; Rolla, Valeria ; Duarte, Rafael S. ; ... More +
Couto de Mello, Karla Gripp ; Queiroz Mello, Fernanda C. ; Borga, Liamar ; Rolla, Valeria ; Duarte, Rafael S. ; Sampaio, Elizabeth P. ; Holland, Steven M. ; Prevots, D. Rebecca ; Dalcolmo, Margareth P. Less -
Description:
To identify clinical and therapeutic features of pulmonary nontuberculous mycobacterial (PNTM) disease, we conducted a retrospective analysis of patients referred to the Brazilian reference center, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil, who received a diagnosis of PNTM during 1993–2011 with at least 1 respiratory culture positive for NTM. Associated conditions included bronchiectasis (21.8%), chronic obstructive pulmonary disease (20.7%), cardiovascular disease (15.5%), AIDS (9.8%), diabetes (9.8%), and hepatitis C (4.6%).Two patients had Hansen disease; 1 had Marfan syndrome. Four mycobacterial species comprised 85.6% of NTM infections: Mycobacterium kansasii, 59 cases (33.9%); M. avium complex, 53 (30.4%); M. abscessus, 23 (13.2%); and M. fortuitum, 14 (8.0%). A total of 42 (24.1%) cases were associated with rapidly growing mycobacteria. In countries with a high prevalence of tuberculosis, PNTM is likely misdiagnosed as tuberculosis, thus showing the need for improved capacity to diagnose mycobacterial disease as well as greater awareness of PNTM disease prevalence.
Subject:
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Adult
Aged
Aged, 80 And Over
Anti-Bacterial Agents
CME
Female
Humans
Lung Diseases
Male
Middle Aged
Mycobacterium Avium Complex
Mycobacterium Infections, Nontuberculous
Mycobacterium Kansasii
Treatment Outcome
Young Adult

Source:
Emerg Infect Dis. 19(3):393-399.
Document Type:
Journal Article
Place as Subject:
Brazil
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
[+]
urn:sha256:6b9b887ec6296c1cc5d4d8294b7c46aa2729f6a7d9cebabcb0b1505aca11bad6
File Type:

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