Pesticide Exposure in Spouses from the Farm Family Exposure Study

Details

• Personal Author:
  Acquavella JF ; Alexander BH ; Baker BA ; Chapman P ; Mandel JS ; Acquavella JF ; Alexander BH ; Baker BA ; Chapman P ; Mandel JS
• Description:
  Background: The Farm Family Exposure Study was designed to characterize pesticide exposure to farm family members around the time of pesticide application. Methods: Farm families were recruited from lists of licensed pesticide applicators in Minnesota and South Carolina. Twenty-four-hour urine samples were collected 1 day before, the day of, and 3 days after application of glyphosate, 2,4-D or chlorpyrifos. A field researcher observed potential exposure opportunities during 106 pesticide applications (10 involving more than 1 pesticide). Spouses completed questionnaires that recorded farm-related activities and other potential routes of pesticide exposures. Results: The spouses had significantly less pesticide exposure than the farmer or children. Only 8% of spouses had detectable urine glyphosate after application. Sixty-eight percent of spouses had quantifiable 2,4-D concentrations postapplication (mean 1.4 ppb) compared with 41% preapplication (mean 1.0 ppb). One spouse had a significant increase in TCP (a chlorpyrifos metabolite) concentrations postapplication although all had detectable levels of TCP (geometric mean 4.5-4.9 ppb). Dose estimates derived from the urine levels will be presented. Conclusion: Spouses had lower urine pesticide levels then applicators or children. Spouses may be exposed during mixing or loading of pesticides but were less likely then children to be involved in mixing or applying pesticides. Pesticide levels varied according to which chemical was applied, and chemical-specific properties are probably important when evaluating exposure. [Description provided by NIOSH]
• Subjects:
  Agriculture Biochemistry Chemistry Chemistry, Analytic Cytology Environmental Monitoring Epidemiology Family Farmers Hazardous Substances Herbicides Hypersensitivity Insecticides Occupational Health Risk Assessment Safety Toxicology Urine

  More +
• Keywords:
  Agricultural-chemicals Agricultural-processes Agricultural-workers Analytical-chemistry Analytical-processes Biochemical-analysis Biohazards Biological-effects Biological-systems Chemical-deposition Chemical-hypersensitivity Chemical-properties Chemical-reactions Children Dose-response Exposure-assessment Exposure-levels Exposure-methods Families Mathematical-models Pesticides-and-agricultural-chemicals Pollution Quantitative-analysis Risk-analysis Statistical-analysis Toxic-dose Toxic-effects Urinalysis Urine-chemistry

  More +
• ISSN:
  0731-3810
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Abstract or Summary ; Abstract or Summary
• Place as Subject:
  California ; Georgia ; Minnesota ; Missouri ; OSHA Region 4 ; OSHA Region 5 ; OSHA Region 7 ; OSHA Region 9
• CIO:
  National Institute for Occupational Safety and Health (NIOSH) ; National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health ; Workplace Safety & Health
• Location:
  North America ; North America
• Volume:
  42
• Issue:
  5
• NIOSHTIC Number:
  nn:20037518
• Citation:
  J Toxicol Clin Toxicol 2004 Sep; 42(5):802
• CAS Registry Number:
  Chlorpyrifos (CAS RN 2921-88-2) ; Chlorpyrifos (CAS RN 2921-88-2)
• Federal Fiscal Year:
  2004
• Performing Organization:
  University of Minnesota Twin Cities
• Peer Reviewed:
  False
• Start Date:
  20050701
• Source Full Name:
  Journal of Toxicology: Clinical Toxicology
• End Date:
  20250630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:e3b9ba1c16eb670e857e6975f130c3b4c19df276188ac16223dda56e87df295b20055ea48718c92ef97e3f1a8df2fb734155bb312865f7fa7b1deadf1cf40125
• Download URL:
  https://stacks.cdc.gov/view/cdc/188599/cdc_188599_DS1.pdf
• File Type:
  [PDF - 66.71 KB ]