The Incidence of Fibromyalgia and Its Associated Comorbidities: A Population-Based Retrospective Cohort Study Based on International Classification of Diseases, 9th Revision Codes

Details

• Personal Author:
  Gren LH ; Harlan GA ; Hegmann KT ; Jones SS ; Lyon JL ; Nkoy FL ; Weir PT
• Description:
  BACKGROUND: The epidemiology of fibromyalgia is poorly defined. The incidence of fibromyalgia has not been determined using a large population base. Previous studies based on prevalence data demonstrated that females are 7 times more likely to have fibromyalgia than males and that the peak age for females is during the childbearing years. OBJECTIVE: We have calculated the incidence rate of fibromyalgia in a large, stable population and determined the strength of association between fibromyalgia and 7 comorbid conditions. METHODS: We conducted a retrospective cohort study of a large, stable health insurance claims database (62,000 nationwide enrollees per year). Claims from 1997 to 2002 were examined using the International Classification of Diseases, 9th Revision, Clinical Modification (ICD-9-CM) codes to identify fibromyalgia cases (ICD code 729.1) and 7 predetermined comorbid conditions. RESULTS: A total of 2595 incident cases of fibromyalgia were identified between 1997 and 2002. Age-adjusted incidence rates were 6.88 cases per 1000 person-years for males and 11.28 cases per 1000 person-years for females. Females were 1.64 times (95% confidence interval = 1.59-1.69) more likely than males to have fibromyalgia. Patients with fibromyalgia were 2.14 to 7.05 times more likely to have one or more of the following comorbid conditions: depression, anxiety, headache, irritable bowel syndrome, chronic fatigue syndrome, systemic lupus erythematosus, and rheumatoid arthritis. CONCLUSION: Females are more likely to be diagnosed with fibromyalgia than males, although to a substantially smaller degree than previously reported, and there are strong associations for comorbid conditions that are commonly thought to be associated with fibromyalgia. [Description provided by NIOSH]
• Subjects:
  Epidemiology Fibrosis Men Morbidity Musculoskeletal System Occupational Health Safety Women
• Keywords:
  Author Keywords: Fibromyalgia Comorbidity Disease-incidence Incidence Morbidity-rates Muscle-tissue Muscles Pain-tolerance Tissue-disorders
• ISSN:
  1076-1608
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  OSHA Region 8 ; Utah
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  124-128
• Volume:
  12
• Issue:
  3
• NIOSHTIC Number:
  nn:20037346
• Citation:
  J Clin Rheumatol 2006 Jun; 12(3):124-128
• Federal Fiscal Year:
  2006
• Performing Organization:
  University of Utah
• Peer Reviewed:
  True
• Start Date:
  20050701
• Source Full Name:
  Journal of Clinical Rheumatology
• End Date:
  20280630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:d76c9f7ca1c9e68193908a05557b25d612affaf1222faf90fd7c1b7fcc5f830fea786ae120ade8e978ff2658f499952d34e9ac2f307fc5d8e641a5d1f9a644bb
• Download URL:
  https://stacks.cdc.gov/view/cdc/188448/cdc_188448_DS1.pdf
• File Type:
  [PDF - 98.51 KB ]