Comorbidity and Primary Treatment for Localized Prostate Cancer: Data from CaPSURE

Details

• Personal Author:
  Arredondo SA ; Broering JM ; Carroll PR ; DuChane J ; Elkin EP ; Marr PL
• Description:
  Purpose: The optimal approach for treating localized prostate cancer remains controversial, leading to a multifactorial decision making process. We characterized the extent to which the presence and number of comorbidities affects treatment for localized prostate cancer. Materials and Methods: Data were abstracted from a longitudinal observational database of men with prostate cancer. A total of 5,149 men diagnosed with localized prostate cancer between 1995 and 2001 were included in this analysis if they had been treated with RP, external beam radiation, brachytherapy, hormonal therapy or surveillance. Comorbidity was assessed through a patient reported checklist of conditions. Multinomial logistic regression was used to determine the OR of the likelihood of receiving each type of therapy. The number of comorbidities and specific comorbidities in patients receiving RP were compared with comorbidities in patients receiving other treatment. Results: The adjusted OR showed a dose response between the number of comorbidities and an increasing probability of any nonRP treatment. In addition, heart disease, stroke or another urinary condition were found to be associated with treatment. Conclusions: Patient comorbidities affect decision making regarding treatment for localized prostate cancer. Urologists and other physicians treating this disease appear to evaluate patient comorbidities when selecting treatment options. [Description provided by NIOSH]
• Subjects:
  Demography Health Care Facilities Workforce And Services Men Neoplasms Occupational Health Risk Assessment Safety Surveys And Questionnaires Urogenital Diseases Urogenital System
• Keywords:
  Author Keywords: Prostate Biological-effects Comorbidity Demographic-characteristics Medical-monitoring Medical-surveys Medical-treatment Physiological-effects Physiological-measurements Physiological-response Practice Guidelines Prostate-cancer Prostatic Neoplasms Questionnaires Risk-analysis Statistical-analysis Surgery

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• ISSN:
  0022-5347
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  California ; Illinois ; OSHA Region 5 ; OSHA Region 9
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  175
• Issue:
  4
• NIOSHTIC Number:
  nn:20037211
• Citation:
  J Urol 2006 Apr; 175(4):1326-1331
• Contact Point Address:
  Peter R. Carroll, 400 Parnassus Avenue, Box 0738, San Francisco, CA 94143
• Email:
  pcarroll@urol.ucsf.edu
• Federal Fiscal Year:
  2006
• Performing Organization:
  University of California, Berkeley
• Peer Reviewed:
  True
• Start Date:
  20050701
• Source Full Name:
  The Journal of Urology
• End Date:
  20250630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:a38ecfc91e459e8af925d20e1707f94a0c77165166c3417ce173b4ec2295fe9713c272812bf15eed50308ff0c5e93b6ee3bf1daa263a49543cd0ce26588499c8
• Download URL:
  https://stacks.cdc.gov/view/cdc/188340/cdc_188340_DS1.pdf
• File Type:
  [PDF - 132.85 KB ]