The Association of Pipe and Cigar Use with Cotinine Levels, Lung Function, and Airflow Obstruction: A Cross-Sectional Study

Details

• Personal Author:
  Barr RG ; Jiang R ; Johnson WC ; MacKenzie, Barbara A. ; Rodriguez J ; Smith LJ
• Description:
  Background: Cigarette smoking is the major cause of chronic obstructive pulmonary disease, but studies on the contribution of other smoking techniques are sparse. Objective: To determine whether pipe and cigar smoking was associated with elevated cotinine levels, decrements in lung function, and increased odds of airflow obstruction. Design: Cross-sectional study. Setting: Population-based sample from 6 U.S. communities. Participants: Men and women aged 48 to 90 years without clinical cardiovascular disease at enrollment who were part of MESA (Multi-Ethnic Study of Atherosclerosis). Measurements: The MESA Lung Study measured spirometry according to American Thoracic Society guidelines and urine cotinine levels by immunoassay on a subsample of MESA. Pipe-years and cigar-years were calculated as years from self-reported age of starting to age of quitting (or to current age in current users) multiplied by pipe-bowls or cigars per day. Results: Of 3528 participants, 9% reported pipe smoking (median, 15 pipe-years), 11% reported cigar smoking (median, 6 cigar-years), and 52% reported cigarette smoking (median, 18 pack-years). Self-reported current pipe and cigar smokers had elevated urine cotinine levels compared with never-smokers. Pipe-years were associated with decrements in FEV(1), and cigar-years were associated with decrements in the FEV(1)-FVC ratio. Participants who smoked pipes or cigars had increased odds of airflow obstruction whether they had also smoked cigarettes (odds ratio, 3.43 [95% CI, 1.75 to 6.71]; P < 0.001) or not (odds ratio, 2.31 [CI, 1.04 to 5.11]; P = 0.039) compared with participants with no smoking history. Limitation: Cross-sectional design. Conclusion: Pipe and cigar smoking increased urine cotinine levels and was associated with decreased lung function and increased odds of airflow obstruction, even in participants who had never smoked cigarettes. [Description provided by NIOSH]
• Subjects:
  Epidemiology Lung Diseases Occupational Health Respiratory Tract Diseases Safety Smokers Tobacco Products
• Keywords:
  Cigarette-smoking Lung-disease Lung-disorders Pulmonary-system-disorders Respiratory-system-disorders Statistical-analysis
• ISSN:
  0003-4819
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  Illinois ; New York ; Ohio ; OSHA Region 10 ; OSHA Region 2 ; OSHA Region 5 ; Washington
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DART - Division of Applied Research and Technology
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  201-210
• Volume:
  152
• Issue:
  4
• NIOSHTIC Number:
  nn:20036493
• Citation:
  Ann Intern Med 2010 Feb; 152(4):201-210
• Federal Fiscal Year:
  2010
• NORA Priority Area:
  Construction
• Peer Reviewed:
  True
• Source Full Name:
  Annals of Internal Medicine
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:0d8984a161c914871c83ef8b16925a12731184d57f3d9849b9d4e0236f7883c8af124fb11142a68a55559225d0405d87891408e0ae72be5087bf73e85ecf2234
• Download URL:
  https://stacks.cdc.gov/view/cdc/187894/cdc_187894_DS1.pdf
• File Type:
  [PDF - 141.92 KB ]