Evaluation of Coumaphos Exposure Among Tick Eradication Workers

Details

• Personal Author:
  Delaney, Lisa J. ; Mueller, Charles A. ; Page, Elena H. ; Thomas, Gregory A.
• Description:
  Objective: To evaluate both the cholinesterase monitoring program and newer field methods of determining coumaphos exposure among tick eradication workers. Methods: Measured blood cholinesterase by the Ellman and field testing methods and tested urine for chlorferon pre- and postshift; conducted personal air sampling, patch sampling of clothing, and wipe sampling of hands for coumaphos. Results: Fifteen workers had normal plasma cholinesterase and acetylcholinesterase levels. No significant changes occurred pre- to postshift. High correlation was found between plasma cholinesterase and acetylcholinesterase levels by field testing and Ellman methods (r = 0.91, P < 0.01 and r = 0.63, P < 0.01, respectively). Chlorferon levels rose 4 to 6 hours after use (P < 0.01). Airborne coumaphos was detected in only one sample, in a trace amount. The majority of patch and hand wipe samples detected coumaphos. Conclusions: Dermal exposure to coumaphos resulted in significant increases in urinary metabolites of coumaphos. [Description provided by NIOSH]
• Subjects:
  Environmental Monitoring Occupational Health Safety Workplace
• Keywords:
  Biological-effects Exposure-assessment Exposure-levels Exposure-methods Work-environment Workplace-studies
• ISSN:
  1076-2752
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  Ohio ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DSHEFS - Division of Surveillance, Hazard Evaluations, and Field Studies
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  131-136
• Volume:
  52
• Issue:
  2
• NIOSHTIC Number:
  nn:20036457
• Citation:
  J Occup Environ Med 2010 Feb; 52(2):131-136
• Contact Point Address:
  Elena Page, MD, MPH, NIOSH/CDC, 4676 Columbia Parkway, Mailstop R-10, Cincinnati, OH 45226
• Email:
  epage@cdc.gov
• CAS Registry Number:
  Coumaphos (CAS RN 56-72-4)
• Federal Fiscal Year:
  2010
• NORA Priority Area:
  Services
• Peer Reviewed:
  True
• Source Full Name:
  Journal of Occupational and Environmental Medicine
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:288f3561578812b1b60de5aba637ab1f2ae6612c7ed2b87917e7b912adaf0516ba2b71f5843fe10b1495e51237658a4ec8f87f6a75758b37a8d0f5f303f706e4
• Download URL:
  https://stacks.cdc.gov/view/cdc/187877/cdc_187877_DS1.pdf
• File Type:
  [PDF - 107.44 KB ]